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In vitro research of anti-HSV-1 activity in different extracts from Pacific oysters Crassostrea gigas ArchiMer
Olicard, Cecile; Didier, Yohann; Marty, Christel; Bourgougnon, Nathalie; Renault, Tristan.
Mortalities related to the detection of Ostreid Herpesvirus 1 (OsHV-1) have been previously reported in France among larvae and spat of the Pacific oyster Crassostrea gigas. Adult oysters appear less sensitive to herpesvirus infections, although OsHV-1 has been detected in adults without signs of disease or mortality. This suggests that the virus is able to persist in its host and that adult oysters may be able to control OsHV-1 infection. Little is known about antiviral substances in invertebrates. The present work concerns the research of antiviral substances in adult oyster C. gigas, where putative antiviral activities were monitored using 3 strategies: (1) in metabolites with variable polarity, (2) in peptidic extracts and (3) in crude haemolymph. In...
Tipo: Text Palavras-chave: Haemolymph; Antiviral peptides; HSV 1; OsHV 1; Antiviral defence; Crassostrea gigas; Oyster.
Ano: 2005 URL: http://archimer.ifremer.fr/doc/2005/publication-2922.pdf
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