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| Vaz,N.M.; Faria,A.M.C. de; Verdolin,B.A.; Silva Neto,A.F.; Menezes,J.S.; Carvalho,C.R.. |
| Current immunological opinion disdains the necessity to define global interconnections between lymphocytes and regards natural autoantibodies and autoreactive T cells as intrinsically pathogenic. Immunological theories address the recognition of foreignness by independent clones of lymphocytes, not the relations among lymphocytes or between lymphocytes and the organism. However, although extremely variable in cellular/molecular composition, the immune system preserves as invariant a set of essential relations among its components and constantly enacts contacts with the organism of which it is a component. These invariant relations are reflected, for example, in the life-long stability of profiles of reactivity of immunoglobulins formed by normal organisms... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Immunobiology; Immune system; Closure; Network; Autopoiesis; Panama blot. |
| Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000100003 |
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| VALENZUELA,CARLOS Y. |
| The synthetic theory of evolution proposes that biotic variations generated by mutation are mostly fixed, lost or maintained polymorphic by natural selection, with a marginal effect due to genetic drift. Based on the theory of autopoiesis some authors have proposed that selection is unable to explain most evolutionary changes, and natural or phenotype drift and epigenesis are the mechanisms that explain most of evolution. This view misunderstands basic evolutionary notions. Selection is a natural process that occurs with or without evolution; it does not explain evolution, it is a factor of the evolutionary process. The concept of autopoiesis implies an invariant condition of living beings, thus, it cannot explain and even less produce evolution conceived... |
| Tipo: Journal article |
Palavras-chave: Autopoiesis; Evolution; Natural drift; Neutral evolution; Selection; Synthetic theory. |
| Ano: 2007 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-078X2007000100009 |
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