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Antifungal compound produced by the cassava endophyte Bacillus pumilus MAIIIM4a Scientia Agricola
Melo,Flávia Mandolesi Pereira de; Fiore,Marli Fátima; Moraes,Luiz Alberto Beraldo de; Silva-Stenico,Maria Estela; Scramin,Shirlei; Teixeira,Manoel de Araújo; Melo,Itamar Soares de.
In the search for new organisms and new secondary metabolites, a study was conducted to evaluate the diversity of endophytic bacteria from ethnovarieties of cassava cultivated by Brazilian Amazon Indian tribes and also to study the secondary metabolites produced by a Bacillus pumilus strain. Sixty seven cassava endophytic bacteria were subjected to 16S rRNA sequencing and FAME analysis. The bacterial profile revealed that 25% of all endophytic isolates belonged to the genus Bacillus. The isolate B. pumilus MAIIIM4a showed a strong inhibitory activity against the fungi Rhizoctonia solani, Pythium aphanidermatum and Sclerotium rolfsii. Secondary metabolites of this strain were extracted using hexane, dichloromethane and ethyl acetate. Extracts were subjected...
Tipo: Info:eu-repo/semantics/article Palavras-chave: ESI-MS/MS; Pumilacidin; Endophytic bacteria; Bioautography.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162009000500002
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Flavonoids of Lonchocarpus montanus A.M.G. Azevedo and biological activity Anais da ABC (AABC)
Magalhães,Aderbal F.; Tozzi,Ana Maria G.A.; Magalhães,Eva G.; Sannomiya,Miriam; Soriano,Maria del Pilar C.; Perez,Mary A.F..
The analysis of root extracts from Lonchocarpus montanus A.M.G. Azevedo resulted in the isolation of twenty three compounds chiefly flavonoids of which five (four flavonoids and one benzophenone) are described for the first time. The molecular structures of the new compounds (1-5) were determined through spectral analysis (UV, IR, MS and NMR) as being: 2'-hydroxy-8-(<FONT FACE=Symbol>a,a</FONT>-dimethylallyl)-2", 2"-dimethylpyrano-(5",6":3',4')-dibenzoylmethane (1), 2'-methoxy-8-(<FONT FACE=Symbol>a, a</FONT>-dimethylallyl)-2", 2"-dimethylpyrano-(5",6":3',4')-dibenzoylmethane (2), 4'-methoxy-2",2"-dimethylpyrano-(5",6":8,7)-flavone (3), 2"-(1-hydroxy-1-methylethyl)-furano-(4",5":8,7)-flavone (4) and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Lonchocarpus montanus A.M.G. Azevedo; Leguminosae; Dibenzoylmethanes; Flavonoids; Flavones; Benzophenone; Bioautography; Artemia salina lethality.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652007000300001
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The potential of an Aspergillus fumigatus Brazilian strain to produce antimicrobial secondary metabolites BJM
Furtado,Niege Araçari Jacometti Cardoso; Fonseca,Maria José Vieira; Bastos,Jairo Kenupp.
During the course of screening for biologically leading active natural products from fungi, a strain of Aspergillus fumigatus was assessed for antimicrobial activity production. Four parameters consisting of medium culture, pH, temperature and time of fermentation were investigated. The extracts from the fungus cultures displayed different TLC profiles and produced, at least, one inhibition zone in the bioautography assays. Overlapping inhibition zones in the range of Rf 0.09 to 0.65 against Kocuria rhizophila were detected in the bioautography assay of the chloroform extract obtained from Jackson's medium culture, initial pH of 6.0 and incubation at 40ºC for 144 hours. However, the obtained extracts by developing the fungus culture in Vogel's medium...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antimicrobial activity; Aspergillus fumigatus; Bioautography; Fermentation conditions.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822005000400010
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