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| Hermabessiere, Ludovic; Dehaut, Alexandre; Paul-pont, Ika; Lacroix, Camille; Jezequel, Ronan; Soudant, Philippe; Duflos, Guillaume. |
| Plastics debris, especially microplastics, have been found worldwide in all marine compartments. Much research has been carried out on adsorbed pollutants on plastic pieces and hydrophobic organic compounds (HOC) associated with microplastics. However, only a few studies have focused on plastic additives. These chemicals are incorporated into plastics from which they can leach out as most of them are not chemically bound. As a consequence of plastic accumulation and fragmentation in oceans, plastic additives could represent an increasing ecotoxicological risk for marine organisms. The present work reviewed the main class of plastic additives identified in the literature, their occurrence in the marine environment, as well as their effects on and transfers... |
| Tipo: Text |
Palavras-chave: Microplastics; Plastic additives; Bisphenol A; Phthalates; Brominated flame retardant. |
| Ano: 2017 |
URL: http://archimer.ifremer.fr/doc/00391/50227/51394.pdf |
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| Lagos-Cabré,Raúl; Moreno,Ricardo D. |
| Bisphenol A [2,2-bis(4-hydroxyphenyl)propane] (BPA), 4-nonylphenol (NP) and di(2-ethylhexyl)phthalate (DEHP), and its metabolite mono-2-ethylhexyl phthalate (MEHP) are chemicals found in plastics, which act as endocrine disruptors (EDs) in animals, including human. EDs act like hormones in the endocrine system, and disrupt the physiologic function of endogenous hormones. Most people are exposed to different endocrine disruptors and concern has been raised about their true effect on reproductive organs. In the testis, they seem to preferentially attack developing testis during puberty rather than adult organs. However, the lack of information about the molecular mechanism, and the apparently controversial effect observed in different models has hampered the... |
| Tipo: Journal article |
Palavras-chave: Testis; Spermatogenesis; Bisphenol A; Nonylphenol; ADAM17. |
| Ano: 2012 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000100001 |
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| Xu,B.L.; Zhao,Q.Z.; Gao,X.Y.; Hou,G.J.. |
| Sex hormones from environmental and physiological sources might play a major role in the pathogenesis of hepatoblastoma in children. This study investigated the effects of estradiol and bisphenol A on the proliferation and telomerase activity of human hepatoblastoma HepG2 cells. The cells were divided into 6 treatment groups: control, bisphenol A, estradiol, anti-estrogen ICI 182,780 (hereinafter ICI), bisphenol A+ICI, and estradiol+ICI. Cell proliferation was measured based on average absorbance using the Cell Counting-8 assay. The cell cycle distribution and apoptotic index were determined by flow cytometry. Telomerase activity was detected by polymerase chain reaction and a telomeric repeat amplification protocol assay. A higher cell density was... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Estradiol; Bisphenol A; HepG2; Telomerase activity. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015001101004 |
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