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| CAMASSA,JOSÉ A.; DIOGO,CAMILA C.; SOUSA,CRISTINA P.; AZEVEDO,JORGE T.; VIEGAS,CARLOS A.; REIS,RUI L.; DOURADO,NUNO; DIAS,ISABEL R.. |
| ABSTRACT Bone turnover markers (BTMs) are product of bone cell activity and are generally divided in bone formation and bone resorption markers. The purpose of this review was to structure the available information on the use of BTMs in studies on small ruminants, especially for monitoring their variations related to diet, exercise, gestation and metabolic lactation state, circadian and seasonal variations, and also during skeletal growth. Pre-clinical and translational studies using BTMs with sheep and goats as animal models in orthopaedic research studies to help in the evaluation of the fracture healing process and osteoporosis research are also described in this review. The available information from the reviewed studies was systematically organized in... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bone formation markers; Bone resorption markers; Bone metabolism; Small ruminants.. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000100231 |
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| Sousa,Cristina P.; Dias,Isabel R.; Lopez-peña,Mónica; Camassa,José A.; Lourenço,Paulo J.; Judas,Fernando M.; Gomes,Manuela E.; Reis,Rui L.. |
| Imaging techniques are the standard method for assessment of fracture healing processes. However, these methods are perhaps not entirely reliable for early detection of complications, the most frequent of these being delayed union and non-union. A prompt diagnosis of such disorders could prevent prolonged patient distress and disability. Efforts should be directed towards the development of new technologies for improving accuracy in diagnosing complications following bone fractures. The variation in the levels of bone turnover markers (BTMs) have been assessed with regard to there ability to predict impaired fracture healing at an early stage, nevertheless the conclusions of some studies are not consensual. In this article the authors have revised the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bone formation markers; Bone resorption markers; Delayed union; Fracture healing; Osteoclast regulatory proteins; Non-union process. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000201049 |
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