|
|
|
|
|
| Louzada-Júnior,P.; Freitas,M.V.C.; Oliveira,R.D.R.; Deghaide,N.H.S.; Conde,R.A.; Bertolo,M.B.; Donadi,E.A.. |
| The objective of the present study was to evaluate the contribution of the shared epitope (SE), the rheumatoid arthritis (RA) protection model, and the occurrence of anti-cyclic citrullinated peptide (anti-CCP) antibodies in RA patients from a genetically diverse population. One hundred and forty Brazilian RA patients and 161 matched controls were typed for HLA-DRB1 alleles using amplified DNA hybridized with sequence-specific oligonucleotide probes or primers. Patients were stratified according to the presence or absence of SE (DRB1*0401, *0404, *0405, *0101, *1001, and *1402), of the DERAA alleles (DRB1*0103, *0402, *1102, *1103, *1301, *1302, and *1304), and X (all other alleles). Anti-CCP antibodies were measured by ELISA. The combined frequency of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Susceptibility to rheumatoid arthritis; HLA; Brazilians; Shared epitope; Anti-cyclic citrullinated peptide. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000600010 |
| |
|
|
| Rodrigues,A.; Rios,M.; Pellegrino Jr.,J.; Costa,F.F.; Castilho,L.. |
| The molecular basis for RHD pseudogene or RHDpsi is a 37-bp insertion in exon 4 of RHD. This insertion, found in two-thirds of D-negative Africans, appears to introduce a stop codon at position 210. The hybrid RHD-CE-Ds, where the 3' end of exon 3 and exons 4 to 8 are derived from RHCE, is associated with the VS+V- phenotype, and leads to a D-negative phenotype in people of African origin. We determined whether Brazilian blood donors of heterogeneous ethnic origin had RHDpsi and RHD-CE-Ds. DNA from 206 blood donors were tested for RHDpsi by a multiplex PCR that detects RHD, RHDpsi and the C and c alleles of RHCE. The RHD genotype was determined by comparison of size of amplified products associated with the RHD gene in both intron 4 and exon 10/3'-UTR. VS... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: RHD pseudogene; RHD-CE-Ds; D-negative phenotype; VS antigen; Brazilians. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000700002 |
| |
|
| |
|
|
| SOUSA,Alessandra Gaspar; MACHADO,Liliane Maria Messias; SILVA,Eduardo Freitas da; COSTA,Teresa Helena Macedo da. |
| Abstract The aim of this study is to describe the characteristics of consumers and non-consumers, the reasons and foods associated with coffee intake among adults from the Federal District, Brazil. This is a cross-sectional population-based survey conducted by telephone interview (n= 1,368). We collected information on detailed coffee intake, socio-demographic aspects and personal characteristics. The coffee had an average daily intake of 319 mL. Individuals were more likely to drink coffee at an older age (68%) and with higher body mass index (58%). The most cited reason for consuming coffee was the “personal pleasure” (48%), followed by “habit / tradition” of consuming coffee. Among non-consumers of this beverage, the main reason was not liking the taste... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Coffee; Consumption; Brazilians; Taste; Beverage. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612016000300432 |
| |
|
|
|
