|
|
|
|
|
| Dang, C.; Gonzalez, P.; Mesmer-dudons, N.; Bonami, J-r; Caill-milly, Nathalie; De Montaudouin, X.. |
| Recently, Manila clam, Ruditapes philippinarum, populations have suffered mortalities in Arcachon Bay (SW France). Mortality was associated with extensive lesions of the posterior adductor muscle, which become progressively brown and calcified. Ultrastructural observations by transmission electron microscopy revealed tissue degradation with necrotized muscle fibres and granulocytomas. Unenveloped virus-like particles (VLPs) were detected in muscle, granulocytic, epithelial and rectal cells. VLPs were abundant in the extracellular space, in the cytoplasm (free or enclosed in vesicles) and in the nucleoplasm of granulocytes. Nuclei and mitochondria of granulocytes displayed changes which suggested reactive oxygen species production and apoptosis induction.... |
| Tipo: Text |
Palavras-chave: Adductor muscle; Apoptosis; Brown muscle disease; Necrosis; Ruditapes philippinarum; Transmission electron microscopy. |
| Ano: 2009 |
URL: https://archimer.ifremer.fr/doc/00000/11130/7991.pdf |
| |
|
|
| Dang, C; De Montaudouin, X; Gonzalez, P; Mesmer Duldons, N; Caill-milly, Nathalie. |
| We describe an emerging pathology, brown muscle disease (BMD), which specifically affects the Manila clam Ruditapes philippinarum in Arcachon Bay (France). BMD induces a transformation of the posterior adductor muscle, which becomes infused by conchiolin and calcified, reducing the ability of clams to bury. The disease affects both types of muscular tissue, with striated muscle becoming affected to a higher degree than smooth muscle. Two indices were created to quantify the symptoms: the Muscle Print Index, used for empty and live shells, and the Final Disease Index, utilized for live clams only. Histological sections were made and observed under light microscopy to examine the muscular damage and to investigate a causal agent. Sections revealed an... |
| Tipo: Text |
Palavras-chave: Light microscopy; Pathology; Adductor muscle; Ruditapes philippinarum; Clam; Brown muscle disease. |
| Ano: 2008 |
URL: https://archimer.ifremer.fr/doc/2008/publication-4556.pdf |
| |
|
|
|
