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	Provedor de dados Arq. Bras. Med. Vet. Zootec. (1) BJMBR (1) Autor Bompadre,T.F.V. (1) Castro,R.V.G. (1) Gering,A.P. (1) Luz,M.A.M. (1) Marques,M.J. (1) Nunes,N. (1) Paula,D.P. (1) Prada,T.C. (1) Santo Neto,H. (1) Silva,P.E.S. (1) Simões,A.P.R. (1) Mais... Palavra-chave Bupivacaine (2) Dog (1) Duchenne muscular dystrophy (1) Epidural catheter (1) Mdx fiber regeneration (1) Muscle degeneration (1) Regional anesthesia (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 2016 (1) 2002 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Evaluation of the cardiopulmonary and antinociceptive effects of bupivacaine administered epidurally at the first lumbar vertebra in awake dogs Arq. Bras. Med. Vet. Zootec. Silva,P.E.S.; Nunes,N.; Gering,A.P.; Prada,T.C.; Simões,A.P.R.; Bompadre,T.F.V.; Castro,R.V.G.; Paula,D.P.. ABSTRACT The aim of this study was to evaluate the effect of epidural bupivacaine administration at the first lumbar vertebra on cardiopulmonary variables, arterial blood gases and anti-nociception. Sixteen healthy female dogs were randomly assigned into two groups based on bupivacaine dose: G1 group, 1mg kg-1 or G2 group, 2mg kg-1, diluted in the same final volume (1mL4kg-1). Cardiopulmonary variables were measured and arterial blood gas was collected (T0), it was repeated 10 minutes after intravenous administration of butorphanol 0.4mg kg -1 (T1). Anesthesia was induced with intravenous etomidate at 2mg kg-1 and the epidural catheter was introduced and placed at the first lumbar vertebra. Thirty minutes later, bupivacaine was administered epidurally.... Tipo: Info:eu-repo/semantics/article Palavras-chave: Bupivacaine; Dog; Epidural catheter; Regional anesthesia. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352016000601395 Impaired regeneration of dystrophin-deficient muscle fibers is caused by exhaustion of myogenic cells BJMBR Luz,M.A.M.; Marques,M.J.; Santo Neto,H.. Duchenne muscular dystrophy is one of the most devastating myopathies. Muscle fibers undergo necrosis and lose their ability to regenerate, and this may be related to increased interstitial fibrosis or the exhaustion of satellite cells. In this study, we used mdx mice, an animal model of Duchenne muscular dystrophy, to assess whether muscle fibers lose their ability to regenerate after repeated cycles of degeneration-regeneration and to establish the role of interstitial fibrosis or exhaustion of satellite cells in this process. Repeated degenerative-regenerative cycles were induced by the injection of bupivacaine (33 mg/kg), a myotoxic agent. Bupivacaine was injected weekly into the right tibialis anterior muscle of male, 8-week-old mdx (N = 20) and... Tipo: Info:eu-repo/semantics/other Palavras-chave: Mdx fiber regeneration; Bupivacaine; Duchenne muscular dystrophy; Muscle degeneration. Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000600009 Registros recuperados: 2 Primeira ... 1 ... Última

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