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Bellini,Marilanda Ferreira; Silva,Ana Elizabete; Varella-Garcia,Marileila. |
This review summarizes the chromosomal changes detected by molecular cytogenetic approaches in esophageal squamous cell carcinoma (ESCC), the ninth most common malignancy in the world. Whole genome analyses of ESCC cell lines and tumors indicated that the most frequent genomic gains occurred at 1, 2q, 3q, 5p, 6p, 7, 8q, 9q, 11q, 12p, 14q, 15q, 16, 17, 18p, 19q, 20q, 22q and X, with focal amplifications at 1q32, 2p16-22, 3q25-28, 5p13-15.3, 7p12-22, 7q21-22, 8q23-24.2, 9q34, 10q21, 11p11.2, 11q13, 13q32, 14q13-14, 14q21, 14q31-32, 15q22-26, 17p11.2, 18p11.2-11.3 and 20p11.2. Recurrent losses involved 3p, 4, 5q, 6q, 7q, 8p, 9, 10p, 12p, 13, 14p, 15p, 18, 19p, 20, 22, Xp and Y. Gains at 5p and 7q, and deletions at 4p, 9p, and 11q were significant prognostic... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: CGH; Esophageal carcinoma; FISH; Genomic imbalances; Molecular cytogenetics. |
Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000200001 |
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Oliveira,Ezequiel A. de; Sassi,Francisco de M. C.; Perez,Manolo F.; Bertollo,Luiz A. C.; Ráb,Petr; Ezaz,Tariq; Hatanaka,Terumi; Viana,Patrik F.; Feldberg,Eliana; Oliveira,Edivaldo H. C. de; Cioffi,Marcelo de B.. |
Abstract The South American giant fishes of the genus Arapaima, commonly known as pirarucu, are one of the most iconic among Osteoglossiformes. Previously cytogenetic studies have identified their karyotype characteristics; however, characterization of cytotaxonomic differentiation across their distribution range remains unknown. In this study, we compared chromosomal characteristics using conventional and molecular cytogenetic protocols in pirarucu populations from the Amazon and Tocantins-Araguaia river basins to verify if there is differentiation among representatives of this genus. Our data revealed that individuals from all populations present the same diploid chromosome number 2n=56 and karyotype composed of 14 pairs of meta- to submetacentric and 14... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: CGH; Chromosome banding; Fish cytotaxonomy; Osteoglossomorpha; RDNA FISH. |
Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-62252020000400201 |
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Neungrutai Promwatee; Monchai Duangjinda; Wuttigrai Boonkum; Banyat Loapaiboon. |
Objective of this study was to detect the SNPs of GHSR, IGFI, cGH and IGFBP2 genes and their association with growth traits (body weight at 0, 4, 8, 12 and 16 weeks of age, ADG during 0-4, 0-8, 0-12 and 0-16 weeks of growth) and carcass trait (breast width) of Thai native chickens (Chee and Pradu Hang Dam). Blood samples were randomly collected from 60 chickens/breed. The genotypes were detected using PCR-RFLP methods with specific primers for each gene. A mixed model was used to analyze the associations of candidate genes with growth traits. In Chee, the GHSR gene was not significantly associated with growth traits, while, the IGFI gene was significantly associated with body weight at 12 and 16 weeks of age and ADG during 0-12 and 0-16 weeks of age. The... |
Tipo: Collection |
Palavras-chave: Thai Native Chicken; IGFI; IGFBP2; CGH; GHSR; Growth trait; ไก่พื้นเมืองไทย; ลักษณะการเจริญเติบโต; การกลายพันธุ์; ยีน; พันธุ์ชี; พันธุ์ประดู่หางดำ; เครื่องหมายพันธุกรรม. |
Ano: 2011 |
URL: http://anchan.lib.ku.ac.th/agnet/handle/001/5214 |
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