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L'acétylcholinestérase, marqueur de neurotoxicité. Application à la surveillance des effets biologiques des polluants chez les organismes marins ArchiMer
Bocquene, Gilles.
Les cholinestérases et particulièrement l'acétylcholinestérase (AChE) constituent la cible privilégiée de nombreuses molécules neurotoxiques notamment des insecticides organophosphorés (OP) et carbamates. La sensibilité des cholinestérases à ces inhibiteurs est aussi complexe que le polymorphisme de ces enzymes. L'utilisation des niveaux d'activité des cholinestérases comme marqueur d'exposition aux neurotoxiques dans le milieu marin implique donc une connaissance approfondie du polymorphisme de i'enzyme, de Ja sensibilité des formes AChE identifiées et des contaminants neurotoxiques susceptibles de provoquer des variations dans l'activité de cette enzyme chez les organismes marins. Aprés une synthèse des connaissances sur le polymorphisme des...
Tipo: Text Palavras-chave: Biomarqueur; Cholinestérases; Pollution marine; Huître; Organophosphorés; Carbamates.
Ano: 1996 URL: http://archimer.ifremer.fr/doc/00443/55435/56950.pdf
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POTENTIAL FARM-LEVEL IMPACTS OF PROPOSED FQPA IMPLEMENTATION: THE TENNESSEE CASE AgEcon
Ray, Daryll E.; Slinsky, Stephen P.; Torre Ugarte, Daniel de la; Tiller, Kelly.
This research estimates farm-level impacts of a potential ban on organophosphates and carbamates under the FQPA. Insecticide expenditure and first- and fifth-year yield impacts are estimated for five Tennessee representative farms. Results indicate that within five years, the ban could reduce net farm income on Tennessee farms by 16 to 46 percent.
Tipo: Conference Paper or Presentation Palavras-chave: FQPA; Organophosphates; Carbamates; Insecticides; Farm-level analysis; Agricultural and Food Policy; Environmental Economics and Policy.
Ano: 1999 URL: http://purl.umn.edu/21654
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Thermostabilisation of human serum butyrylcholinesterase for detection of its inhibitors in water and biological fluids BABT
Jaganathan,Lakshmanan; Boopathy,Rathanam.
The ability of gelatine-trehalose to convert the normally fragile, dry human serum BChE into a thermostable enzyme and its use in the detection of cholinesterase inhibitors in water and biological fluids is described. Gelatine or trehalose alone is unable to protect the dry enzyme against exposure to high temperature, while a combination of gelatine and trehalose were able to protect the enzyme activity against prolonged exposure to temperature as high as +50°C. A method for rapid, simple and inexpensive means of screening for cholinesterase inhibitors such as carbamates and organophosphates in water, vegetables and human blood has been developed.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Butyrylcholinesterase; Carbamates; Cholinesterase; Gelatine; Organophosphorus; Trehalose.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89131999000300012
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