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| SHU,ZHIMING; WU,TIANTIAN; SHAHEN,MOHAMED; GUO,ZIHU; SHU,JIA; WANG,HE; SHAR,AKHTAR H.; FARAG,MAYADA R.; ALAGAWANY,MAHMOUD; EL-HACK,MOHAMED E. ABD; LIU,CHAOBIN. |
| Abstract: Cardiovascular diseases (CVDs) are leading causes of death in the world, owing to noticeable incidence and mortality. Traditional Chinese Medicine (TCM) SINI Decoction (SND) is used to prevent and treat CVDs, which has attracted extensive attention for its moderate and little side effects. However, the involved molecular mechanisms are exceedingly complicated and remain unclear. Systems pharmacology, as a novel approach that integrates systems biology and pharmacology plays a significant role in investigating the molecular mechanism of TCM. In systems pharmacology approach, we use to systematically uncover the mechanisms of action in Chinese medicinal formula SND as an effective treatment for CVDs, which mainly includes:1) molecular database... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Systems pharmacology; SINI Decoction; Cardiovascular Diseases; Molecular mechanisms; Traditional Chinese herbs. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000500804 |
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