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| Silva,F.B.; Romero,W.G.; Carvalho,A.L.R.; Borgo,M.V.; Amorim,M.H.C.; Gouvea,S.A.; Abreu,G.R.. |
| The objective of this study was to evaluate the effect of tamoxifen on the plasma concentration of NT-pro-B-type natriuretic peptide (NT-proBNP) in women undergoing chemotherapy for breast cancer and to correlate changes in NT-proBNP with the left ventricular ejection fraction (LVEF). Over a period of 12 months, we followed 60 women with a diagnosis of breast cancer. The patients were separated into a group that received only chemotherapy (n=23), a group that received chemotherapy + tamoxifen (n=21), and a group that received only tamoxifen (n=16). Plasma levels of NT-proBNP were assessed at 0 (T0), 6 (T6), and 12 (T12) months of treatment, and echocardiography data were assessed at T0 and T12. Plasma NT-proBNP levels were increased in the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cardiovascular risk profile; Adjuvant chemotherapy; Hormone therapy; NT-B-proBNP; Ecocardiography. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000200154 |
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