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Chronic Stress Effects on Adrenal Cortex Cellular Proliferation in Pregnant Rats International Journal of Morphology
Bozzo,Aída Andrea; Soñez,Carlos Alberto; Monedero Cobeta,Ignacio; Avila,Rodolfo; Rolando,Alicia Nélida; Romanini,María Cristina; Lazarte,Mario; Gauna,Héctor Fernando; Mugnaini,María Teresa.
Chronic stress by immobilization during pregnancy may cause alterations in mechanisms maintaining homeostasis in the adrenal gland. The objective of this study was to quantify cellular proliferation index in the adrenal cortex during pregnancy second half and assess the effects of chronic stress on it. Adrenal cortex proliferation index in stressed rats showed a significant decrease at 12 and 17 days of gestation, while at day 21 it did not show differences with the control treatments. Moreover, proliferation index of reticular zones in control and experimental rats, exhibited a significant reduction in comparison to glomerular and fascicular zones of adrenal cortex during the three gestation days studied. In conclusion, chronic stress by immobilization...
Tipo: Journal article Palavras-chave: Chronic stress; Cellular proliferation; Adrenal cortex; Pregnancy.
Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000400013
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Cell proliferation of the ileum intestinal mucosa of diabetic rats treated with ascorbic acid Biocell
Nelisis Zanoni,Jacqueline; Fernandes Pereira,Renata Virginia.
The objective of this work was to evaluate the effect of the ascorbic acid supplementation on the cellular proliferation on the ileum mucosa of diabetic rats. Fifteen 90-days rats were divided in the groups: control, diabetic and diabetic supplemented with ascorbic acid (DA). Two hours prior the sacrifice, they were injected with Vincristin. Semi-seriate histological cuts stained with HE were accomplished. About 2500 crypt cells from the intestinal mucosa were counted in order to obtain the metaphasic indexes. The height and depth of 30 villi and 30 crypts were measured for each animal, respectively. The metaphasic indexes showed no significant changes when we compared the three groups: 20.2 ± 0.7 (control), 18 ± 1.9 (diabetic) and 17 ± 1.4 (DA) (p >...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ascorbic acid; Diabetes mellitus; Lleum; Cellular proliferation.
Ano: 2008 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452008000200001
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Influence of the neural tube/notochord complex on MyoD expression and cellular proliferation in chicken embryos BJMBR
Alves,H.J.; Alvares,L.E.; Gabriel,J.E.; Coutinho,L.L..
Important advances have been made in understanding the genetic processes that control skeletal muscle formation. Studies conducted on quails detected a delay in the myogenic program of animals selected for high growth rates. These studies have led to the hypothesis that a delay in myogenesis would allow somitic cells to proliferate longer and consequently increase the number of embryonic myoblasts. To test this hypothesis, recently segmented somites and part of the unsegmented paraxial mesoderm were separated from the neural tube/notochord complex in HH12 chicken embryos. In situ hybridization and competitive RT-PCR revealed that MyoD transcripts, which are responsible for myoblast determination, were absent in somites separated from neural tube/notochord...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chicken development; MyoD; Myogenesis; In situ hybridization; BrdU; Cellular proliferation.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000200005
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Humoral and cellular immune responses to Blomia tropicalis and concanavalin A-binding fractions in atopic patients BJMBR
Alves,R.; Silva,D.A.O.; Fernandes,J.F.C.; Almeida,K.C.; Ynoue,L.H.; Bernardes,C.T.V.; Moreira,P.F.S.; Gennari-Cardoso,M.L.; Sung,S.J.; Taketomi,E.A..
Blomia tropicalis, Dermatophagoides pteronyssinus and D. farinae are prevalent house dust mites. Concanavalin A-binding components derived from B. tropicalis (Bt-ConA extract) are highly immunogenic in allergic diseases. The aim of the present study was to evaluate the humoral and cellular immune responses to B. tropicalis in mite-sensitized patients. A total of 137 patients with allergic rhinitis with/without asthma and 109 non-atopic subjects were selected and analyzed by the skin prick test, and for total serum IgE and specific IgE levels to both Bt-total and Bt-ConA extracts, their proliferative response and cytokine (IFN-γ and IL-5) production by peripheral blood mononuclear cells (PBMC) stimulated with both extracts. Skin prick test showed that 70%...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Blomia tropicalis; Concanavalin A; Cellular proliferation; IFN-γ; IL-5; Immunoglobulin E.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000900006
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