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Epigenetically facilitated mutational assimilation: epigenetics as a hub within the inclusive evolutionary synthesis ArchiMer
Danchin, Etienne; Pocheville, Arnaud; Rey, Olivier; Pujol, Benoit; Blanchet, Simon.
After decades of debate about the existence of non-genetic inheritance, the focus is now slowly shifting towards dissecting its underlying mechanisms. Here, we propose a new mechanism that, by integrating non-genetic and genetic inheritance, may help build the long-sought inclusive vision of evolution. After briefly reviewing the wealth of evidence documenting the existence and ubiquity of non-genetic inheritance in a table, we review the categories of mechanisms of parent-offspring resemblance that underlie inheritance. We then review several lines of argument for the existence of interactions between non-genetic and genetic components of inheritance, leading to a discussion of the contrasting timescales of action of non-genetic and genetic inheritance....
Tipo: Text Palavras-chave: Non-genetic inheritance; Inclusive heritability; Epigenetics; Central dogma; Genetic assimilation; Mutation randomness; Inclusive evolutionary synthesis.
Ano: 2019 URL: https://archimer.ifremer.fr/doc/00479/59037/62430.pdf
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