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ACOSTA-RIVERO,NELSON; POUTOU,JOANNA; ÁLVAREZ-LAJONCHERE,LIZ; GUERRA,IVIS; AGUILERA,YARAIMA; MUSACCHIO,ALEXIS; RODRÍGUEZ,ARMANDO; AGUILAR,JULIO C; FALCON,VIVIANA; ÁLVAREZ-OBREGON,JULIO C; SORIA,YORDANKA; TORRES,DINORAH; LINARES,MARBELIS; PÉREZ,ÁNGEL; MORALES-GRILLO,JUAN; DUEÑAS -CARRERA,SANTIAGO. |
In the present work, immunogenicity of recombinant in vitro assembled hepatitis C virus core particles, HCcAg.120-VLPs, either alone or in combination with different adjuvants was evaluated in BALB/c mice. HCcAg.120-VLPs induced high titers of anti-HCcAg.120 antibodies and virus-specific cellular immune responses. Particularly, HCcAg.120-VLPs induced specific delayed type hypersensitivity, and generated a predominant T helper 1 cytokine pro file in immunized mice. In addition, HCcAg.120-VLPs prime splenocytes proliferate in vitro against different HCcAg.120-specific peptides, depending on either the immunization route or the adjuvant used. Remarkably, immunization with HCcAg.120-VLPs/Montanide ISA888 formulation resulted in a significant control of... |
Tipo: Journal article |
Palavras-chave: Challenge; HCV; Immunity; Adjuvant; Capsid. |
Ano: 2009 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000100005 |
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Kalman, Zoltan. |
Nem állt meg a negatív tendencia, a legfrissebb adatok szerint a világon az éhezők száma tovább növekszik. Egybehangzó vélemények szerint a fő élelmezésbiztonsági probléma nem a megtermelt élelmiszer hiánya, hanem annak nem megfelelő elosztása. Ivóvíz, valamint elegendő mennyiségű, biztonságos, megfelelő minőségű és tápanyag-összetételű élelmiszer biztosítása alapvető emberi jog a Föld minden lakója számára. Ennek megteremtése a jelen és jövő generációk számára napjaink egyik legnagyobb kihívása, amelyre megoldást találni nemcsak erkölcsi kötelesség, hanem elengedhetetlenül fontos a világ békéjének és biztonságának a megteremtéséhez is. A Világbank, az ENSZ szervezetek (FAO, IFAD, IFPRI, WFP) és az IFPRI helyzetértékelésében sok a hasonló vonás, mind az... |
Tipo: Journal Article |
Palavras-chave: Kihívás; Éhezés; Élelmiszer; Elosztás; Biztonság; Challenge; Starving; Food; Distribution; Safety; Agricultural and Food Policy; Community/Rural/Urban Development. |
Ano: 2010 |
URL: http://purl.umn.edu/99132 |
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Scanavini Neto,H; Ito,NMK; Miyaji,CI; Lima,E de A; Okabayashi,S; Corrêa,ARA; Eleutério,GC; Zuanaze,MA. |
IBDV Gm 11 (Simbios eleven-molecular group) has been detected since 1997 in many farms of commercial broilers and layers causing high mortality (2 to 15%) and severe macro and microscopic damage in cloacal bursae, spleen, thymus, kidney and liver. Five serial passages of 2050/97-Gm 11 IBDV sample by CAM route in SPF chicken's embryonated eggs did not elicit increased embryo mortality. High mortality (100%) of 21 day-old SPF leghorn chickens and severe bursal and splenic lesions were seen from 24 up to 48 hours after eye-drop inoculation of 2050/97 strain (50 mL of 10-2 dilution of 10% bursae homogenate). Mortality was not detected when vaccinated SPF and broiler chickens were inoculated. One dead bird was found among ten challenged unvaccinated broilers.... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Challenge; Histopathology; IBD; Pathogenicity; Serology. |
Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2004000100006 |
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Manafi,Milad; Hedayati,Mahdi; Khalaji,Saeed; Kamely,Mohammad. |
ABSTRACT The effect of a non-antibiotic growth-promoting component composed of natural phytomolecules, direct-fed microbials, glucomannan oligosaccharides, and organic acids on the performance, intestinal morphology and microbiology, plasma biochemistry, enzyme activities, visceral organ weights, and immune response of commercial broilers challenged with Escherichia coli was investigated. Three hundred and sixty one-day old male Ross 308 broiler chicks were randomly divided into basal diet (control, CON); control plus 0.5 mL of culture materials containing 108 cfu/mL of E. coli (E. coli); control with 400 mg/kg bacitracin methylene disalicylate (an antibiotic growth promoter, AGP); control plus 1000 g/t of feed of a blended mixture of natural feed... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Body weight; Challenge; Chicks; Natural feed additive. |
Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982016001200745 |
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