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| GARCIA,CHARLENE S.C.; MENTI,CAROLINE; LAMBERT,ANA PAULA F.; BARCELLOS,THIAGO; MOURA,SIDNEI; CALLONI,CAROLINE; BRANCO,CÁTIA S.; SALVADOR,MIRIAN; ROESCH-ELY,MARIANA; HENRIQUES,JOÃO A.P.. |
| ABSTRACT Salvia officinalis (Lamiaceae) has been used in south of Brazil as a diary homemade, in food condiment and tea-beverage used for the treatment of several disorders. The objective of this study was to characterize chemical compounds in the hydroalcoholic (ExtHS) and aqueous (ExtAS) extract from Salvia officinalis (L.) by gas chromatography-mass spectrometry (GC-MS) and by high-resolution electrospray ionization mass spectrometry (ESI-QTOF MS/MS), evaluate in vitro ability to scavenge the free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH•) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS•+), catalase (CAT-like) and superoxide dismutase (SOD-like) activity, moreover cytotoxic by MTT assay, alterations on cell morphology by giemsa and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidant; Apoptosis; Cancer; Chemical compounds; Salvia officinalis (L. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000100281 |
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| Regalado, E.L.; Laguna, A.; Martínez, J.R.. |
| Las esponjas marinas (Porifera) han atraído la atención de un gran número de científicos alrededor del mundo. Estos animales y sus simbiontes utilizan mecanismos de defensa química, basados en la producción de compuestos biologicamente activos que utlizan para protegerse de posibles depredadores. Son considerados una mina de oro para los químicos y se han descubierto más de 6000 estructuras novedosas, muchas de ellas con enormes aplicaciones biomédicas, fundamentalmente contra el cáncer, pero también contra diversas bacterias, virus y otras enfermedades. Algunos de los fármacos derivados de esponjas se encuentran disponibles en el mercado, tal es el caso Ara-A (antiviral) y de la Ara-C (antitumoral), pero existen diversos compuestos bioactivos en... |
| Tipo: Journal Contribution |
Palavras-chave: Sponges; Chemical compounds; Bioactive compounds; Chemical compounds; Sponges; Http://aims.fao.org/aos/agrovoc/c_49870; Http://aims.fao.org/aos/agrovoc/c_7321. |
| Ano: 2010 |
URL: http://hdl.handle.net/1834/4039 |
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| Nogueiras, C.; Spengler, I.; Guerra, J.O.; Ortiz, Y.; Torres, S.; García, T.H.; Romeu, C.R.; Regalado, E.L.; González, T.A.; Perera, W.H.; Lacret, R.. |
| Interest in natural products as a source for innovation in drug discovery and agrochemicals is still growing worldwide. Natural products, whose immense diversity has been appreciated for many years, may become in a rich source of novel chemical structures. Our country is a rich source of both biological and chemical diversity which may be useful as a source of novel chemical structures. Even when natural products have been used as medicinal agents for many years in Cuba, their use as agrochemicals are still limited. Thus, the present review focuses on recent advances in the studies on natural products performed by the “Centro de Estudios de Productos Naturales, CEPN” during the past ten years, highlighting on those with potential use as biomedical... |
| Tipo: Journal Contribution |
Palavras-chave: Products; Chemical compounds; Bioactive compounds; Products; Chemical compounds; Http://aims.fao.org/aos/agrovoc/c_6211; Http://aims.fao.org/aos/agrovoc/c_49870. |
| Ano: 2010 |
URL: http://hdl.handle.net/1834/3986 |
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