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	Provedor de dados BJPS (1) Autor Akingbala,Oluwatomi (1) Okunlola,Adenike (1) Palavra-chave Acid hydrolysis (1) Chinese yam/binding properties (1) Chinese yam/starch (1) Dioscorea oppositifolia/pharmaceutics (1) Drugs/release (1) Factorial design (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Ano 2013 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Characterization and evaluation of acid-modified starch of Dioscorea oppositifolia (Chinese yam) as a binder in chloroquine phosphate tablets BJPS Okunlola,Adenike; Akingbala,Oluwatomi. Chinese yam (Dioscorea oppositifolia) starch modified by acid hydrolysis was characterized and compared with native starch as a binder in chloroquine phosphate tablet formulations. The physicochemical and compressional properties (using density measurements and the Heckel and Kawakita equations) of modified Chinese yam starch were determined, and its quantitative effects as a binder on the mechanical and release properties of chloroquine phosphate were analyzed using a 2³ full factorial design. The nature (X1), concentration of starch (X2) and packing fraction (X3) were taken as independent variables and the crushing strength-friability ratio (CSFR), disintegration time (DT) and dissolution time (t80) as dependent variables. Acid-modified Chinese yam... Tipo: Info:eu-repo/semantics/article Palavras-chave: Acid hydrolysis; Chinese yam/starch; Chinese yam/binding properties; Factorial design; Drugs/release; Dioscorea oppositifolia/pharmaceutics. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000400009 Registros recuperados: 1 Primeira ... 1 ... Última

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