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	Provedor de dados J. Venom. Anim. Toxins incl. Trop. Dis. (2) Autor Andreosso,Athena (1) Carrette,T. (1) Seymour,J. (1) Seymour,Jamie E (1) Smout,Michael J (1) Palavra-chave Chironex fleckeri (2) Venom (2) Antivenom (1) Cardiac function (1) Cherax quadricarinatus (1) Chiropsalmus sp (1) Cubozoan (1) Dose–response curve (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2014 (1) 2006 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Cardiotoxic effects of venoms from Chironex fleckeri and Chiropsalmus sp. on an invertebrate model J. Venom. Anim. Toxins incl. Trop. Dis. Carrette,T.; Seymour,J.. Extracted venoms from two species of cubozoan, Chironex fleckeri (C. fleckeri)and Chiropsalmus sp., were injected into the freshwater crayfish Cherax quadricarinatus (C. quadricarinatus). By means of a Vascular Doppler, the cardiac parameters heart rate and contraction amplitude were recorded, with the theoretical total heart output calculated from these two recordings. Cherax quadricarinatus reflects prey items utilized by these two species in the wild and so comparisons of venom action on this animal have greater ecological relevance than those of previous mammalian models used. While the results of this study reflect previous research showing that the overall potency of C. fleckeri venom is greater than that of Chiropsalmus sp. venom, the action of the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cubozoan; Venom; Cardiac function; Cherax quadricarinatus; Chironex fleckeri; Chiropsalmus sp. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000200007 Dose and time dependence of box jellyfish antivenom J. Venom. Anim. Toxins incl. Trop. Dis. Andreosso,Athena; Smout,Michael J; Seymour,Jamie E. Background The effectiveness of the currently available box jellyfish (Chironex fleckeri) antivenom has been subject of debate for many years. To assess whether the box jellyfish antivenom has the ability to attenuate venom-induced damage at cellular level, the present study analyzed the dose and time dependence of the antivenom in a cell-based assay.Methods Different doses of antivenom were added to venom and subsequently administered to cells and the cell index was measured using xCelligence Technology (ACEA Biosciences). Similarly, antivenom and venom were incubated over different time periods and cell survival measured as stated above. For both experiments, the cell index was plotted as a measure of cell survival against the dose or incubation time and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Chironex fleckeri; Antivenom; Venom; Dose–response curve. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200335 Registros recuperados: 2 Primeira ... 1 ... Última

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