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	Provedor de dados 48 (1) 56 (1) 74 (1) 89 (1) Autor Brunetti,Iguatemy L. (1) Coelho,J.C. (1) Cruzes,Vania M. (1) Deng,Q (1) Deng,X (1) Giugliani,R. (1) Liu,N (1) Luo,Y (1) Moretti-Ferreira,Danilo (1) Otto,Paulo A. (1) RIGOTTI,ATTILIO (1) Scalco,F.B. (1) Scalco,Fernanda B. (1) Shi,H (1) Tobo,P. (1) Mais... Palavra-chave Cholesterol metabolism (4) 7-dehydrocholesterol (1) Atherosclerosis (1) HMGR pathway (1) Lactic acid bacteria (1) Laying hens (1) Lipoprotein (1) Lysosomal storage disorders (1) Niemann-Pick disease (1) Scavenger receptor (1) Selective cholesterol uptake (1) Smith-Lemli-Opitz syndrome (1) Sphingomyelinase (1) Yolk components (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Journal article (1) Ano 2020 (1) 2006 (1) 2000 (1) 1999 (1) País Brazil (3) Chile (1) Idioma Inglês (4)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 4 Primeira ... 1 ... Última Scavenger Receptors and Atherosclerosis 48 RIGOTTI,ATTILIO. Scavenger receptors were discovered as cell surface proteins capable of binding and internalization of modified lipoproteins. These receptors exhibit a broad ligand binding specificity including potential physiological and pathophysiological ligands other than modified lipoproteins. Different classes of scavenger receptors have been identified, and their relevance in normal and pathological conditions is under investigation. Recent in vitro and in vivo studies strongly support the role of class A and class B scavenger receptors in lipid transport atherogenesis Tipo: Journal article Palavras-chave: Atherosclerosis; Cholesterol metabolism; Lipoprotein; Scavenger receptor; Selective cholesterol uptake. Ano: 2000 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000200009 Effect of dimethylsulfoxide on sphingomyelinase activity and cholesterol metabolism in Niemann-Pick type C fibroblasts 56 Scalco,F.B.; Giugliani,R.; Tobo,P.; Coelho,J.C.. Niemann-Pick type C (NPC) fibroblasts present a large concentration of cholesterol in their cytoplasm due to a still unidentified deficiency in cholesterol metabolism. The influence of dimethylsulfoxide (DMSO) on the amount of intracellular cholesterol was measured in 8 cultures of normal fibroblasts and in 7 fibroblast cultures from NPC patients. DMSO was added to the fibroblast cultures at three different concentrations (1, 2 and 4%, v/v) and the cultures were incubated for 24 h. Sphingomyelinase activity was significantly increased in both groups of cells only when incubated with 2% DMSO (59.4 ± 9.1 and 77.0 ± 9.1 nmol h-1 mg protein-1, controls without and with 2% DMSO, respectively; 47.7 ± 5.2 and 55.8 ± 4.1 nmol h-1 mg protein-1, NPC without and with... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cholesterol metabolism; Sphingomyelinase; Niemann-Pick disease; Lysosomal storage disorders. Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000100003 Smith-Lemli-Opitz syndrome: clinical and biochemical findings in Brazilian patients 74 Scalco,Fernanda B.; Otto,Paulo A.; Brunetti,Iguatemy L.; Cruzes,Vania M.; Moretti-Ferreira,Danilo. Smith-Lemli-Opitz syndrome (SLOS) or RSH syndrome comprises multiple congenital anomalies and mental retardation. The underlying defect is a deficiency in the activity of delta7-sterol reductase, which decreases cholesterol and increases 7-dehydrocholesterol (7-DHC) levels. Our aim was to identify and evaluate the frequency of SLOS manifestations in a group of Brazilian patients. Based on our own data and those reported previously, we present a simple method that allows the estimation of probabilities favoring the diagnosis of SLOS. We evaluated 30 patients clinically and determined their plasma levels of cholesterol and 7-dehydrocholesterol. In 11 patients, the diagnosis was confirmed by ultraviolet spectrophotometry (UV). Of 19 patients with normal... Tipo: Info:eu-repo/semantics/article Palavras-chave: Smith-Lemli-Opitz syndrome; Cholesterol metabolism; 7-dehydrocholesterol. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572006000300003 Dietary Lactic Acid Bacteria Modulate Yolk Components and Cholesterol Metabolism by Hmgr Pathway in Laying Hens 89 Deng,Q; Shi,H; Luo,Y; Liu,N; Deng,X. ABSTRACT This study aimed to investigate the effect of dietary lactic acid bacteria (LAB) on egg production, yolk components, cholesterol metabolism, and enterohepatic circulation of bile acids in hens. Four treatment diets included a control and LAB added at 3 × 105 (low), 3 × 107 (medium), or 3 × 109 (high) cfu/kg. The treatment LAB contained equal amounts of Lactobacillus acidophilus, Lactobacillus plantarum, and Enterococcus faecium. Results showed that high LAB increased (p<0.05) laying rate, egg mass, and yolk phospholipid, but decreased (p<0.05) yolk triglyceride and phosvitin. Diets with LAB decreased (p<0.05) yolk and serum cholesterol content, and serum bile acid by 9.3 to 39.9%. In liver, high LAB downregulated (p<0.05) mRNA... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cholesterol metabolism; HMGR pathway; Lactic acid bacteria; Laying hens; Yolk components. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2020000300303 Registros recuperados: 4 Primeira ... 1 ... Última

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