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	Provedor de dados BJMBR (1) Autor Ferriani,R.A. (1) Martelli,L. (1) Meola,J. (1) Rosa e Silva,J.C. (1) Santos,S.A. (1) Squire,J.A. (1) Veiga-Castelli,L.C. (1) Yoshimoto,M. (1) Mais... Palavra-chave Chromosomal imbalances (1) Comparative genomic hybridization (1) Endometrioma (1) Endometriosis (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2010 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Genomic alterations detected by comparative genomic hybridization in ovarian endometriomas BJMBR Veiga-Castelli,L.C.; Rosa e Silva,J.C.; Meola,J.; Ferriani,R.A.; Yoshimoto,M.; Santos,S.A.; Squire,J.A.; Martelli,L.. Endometriosis is a complex and multifactorial disease. Chromosomal imbalance screening in endometriotic tissue can be used to detect hot-spot regions in the search for a possible genetic marker for endometriosis. The objective of the present study was to detect chromosomal imbalances by comparative genomic hybridization (CGH) in ectopic tissue samples from ovarian endometriomas and eutopic tissue from the same patients. We evaluated 10 ovarian endometriotic tissues and 10 eutopic endometrial tissues by metaphase CGH. CGH was prepared with normal and test DNA enzymatically digested, ligated to adaptors and amplified by PCR. A second PCR was performed for DNA labeling. Equal amounts of both normal and test-labeled DNA were hybridized in human normal... Tipo: Info:eu-repo/semantics/article Palavras-chave: Endometrioma; Endometriosis; Comparative genomic hybridization; Chromosomal imbalances. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000800014 Registros recuperados: 1 Primeira ... 1 ... Última

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