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	Provedor de dados Biol. Res. (1) BJMBR (1) Autor Clarke,J.A. (1) Daly,M. de B. (1) Ead,H.W. (1) Hennessy,E.M. (1) Marshall,J.M. (1) Miserocchi,Giuseppe (1) Panariti,Alice (1) Rivolta,Ilaria (1) Mais... Palavra-chave Chronic hypoxia (2) Hypoxia-inducible Factor (1) Lung (1) Morphology (1) Prolyl Hydroxylase Domain proteins (1) RT-PCR (1) Rat carotid body (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Journal article (1) Ano 2013 (1) 2000 (1) País Brazil (1) Chile (1) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última mRNA expression profile of selected oxygen sensing genes in the lung during recovery from chronic hypoxia Biol. Res. Panariti,Alice; Miserocchi,Giuseppe; Rivolta,Ilaria. This study analyzed the time dependence decay of the mRNA of selected genes important for the hypoxia response. The genes chosen were the two isoforms of hypoxia-inducible factors, the three isoforms of the prolyl hydroxylase domain protein, the vascular endothelial growth factor and endothelial nitric oxide synthase. mRNA and proteins were extracted from lungs obtained from control, hypoxic and 15 minutes normoxic recovered rats and analyzed by Real-time RT-PCR or by the Western Blot technique. Results indicated that in normoxia isoform 2á was the more represented hypoxia-inducible factor mRNA, and among the prolyl hydroxylase domain transcripts, isoform 3 was the least abundant. Moreover, in chronic hypoxia only hypoxia-inducible factor 1α and... Tipo: Journal article Palavras-chave: Chronic hypoxia; Hypoxia-inducible Factor; Prolyl Hydroxylase Domain proteins; Lung; RT-PCR. Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602013000200008 Quantitative studies of the vasculature of the carotid body in the chronically hypoxic rat BJMBR Clarke,J.A.; Daly,M. de B.; Marshall,J.M.; Ead,H.W.; Hennessy,E.M.. The carotid bodies of rats made chronically hypoxic by breathing 12% O2 in a normobaric chamber (inspired PO2 91 mmHg) were compared with those of controls. Serial 5-µm sections of the organs were examined using an interactive image analysis system. The total volume of the carotid bodies was increased by 64%. The total vascular volume rose by 103% and was likely due to an increase in size of the large vessels (>12 µm lumen diameter) because the small vessel (5-12 µm lumen diameter) volume did not increase significantly while the small vessel density tended to decrease. The extravascular volume was increased by 57%. Expressed as a percentage of the total volume of the organ, the total vascular volume did not change, but the small vessel volume was... Tipo: Info:eu-repo/semantics/article Palavras-chave: Rat carotid body; Morphology; Chronic hypoxia. Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000300012 Registros recuperados: 2 Primeira ... 1 ... Última

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