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	Provedor de dados BABT (1) Autor Krishnamoorthy,Kannan (1) Landge,Anil Vijay (1) Palavra-chave Clostridium novyi-NT (1) Collagenase (1) Fibro-proliferative disorders (1) Response Surface Methodology (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2018 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Statistical Optimisation of Fermentation Media for Novel Clostridium novyi -NT Using Response Surface Methodology. BABT Krishnamoorthy,Kannan; Landge,Anil Vijay. ABSTRACT Clostridial collagenase is recognized as one of the important proteolytic enzymes used in treatment of varieties of fibro-proliferative disorders. The present work aimed to optimise the biomass concentration and collagenase enzyme activity of novel bacilli Clostridium novyi-NT. The response surface methodology tool was used to identify the optimal fermentation parameters. Central composite design (CCD) was applied with respect to three influencing factors - pH, proteose peptone and trypticase soya broth. These factors showed significant effect on the overall biomass concentration and collagenase enzyme activity (p<0.05). The maximum biomass concentration in terms of absorbance and collagenase activity (of crude enzyme) was achieved and recorded... Tipo: Info:eu-repo/semantics/article Palavras-chave: Collagenase; Clostridium novyi-NT; Fibro-proliferative disorders; Response Surface Methodology. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100429 Registros recuperados: 1 Primeira ... 1 ... Última

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