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A defective mutant of Salmonella enterica Serovar Gallinarum in cobalamin biosynthesis is avirulent in chickens BJM
Paiva,Jacqueline Boldrin de; Penha Filho,Rafael Antonio Casarin; Arguello,Yuli Melisa Sierra; Berchieri Junior,Ângelo; Lemos,Manuel Victor Franco; Barrow,Paul A..
Salmonella enterica serovar Gallinarum (SG) is a fowl typhoid agent in chickens and is a severe disease with worldwide economic impact as its mortality may reach up to 80%. It is one of a small group of serovars that typically produces typhoid-like infections in a narrow range of host species and which therefore represents a good model for human typhoid. The survival mechanisms are not considered to be virulent mechanisms but are essential for the life of the bacterium. Mutants of Salmonella Gallinarum containing defective genes, related to cobalamin biosynthesis and which Salmonella spp. has to be produced to survive when it is in an anaerobic environment, were produced in this study. Salmonella Gallinarum is an intracellular parasite. Therefore, this...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Salmonella Gallinarum; Cobalamin biosynthesis; Attenuated strain; CbiA and cobS genes; CbiA; CobS.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822009000300012
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