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	Provedor de dados Anais da ABC (AABC) (1) BJMBR (1) Autor Canavarro,S. (1) HOKOÇ,JAN NORA (1) MARTINEZ,ANA M. B. (1) Martinez,A.M.B. (1) NARCISO,MARCELO S. (1) Palavra-chave Crush lesion (2) Dark degeneration (1) Freeze-fracture (1) Marsupial (1) Myelin breakdown (1) Nerve fiber (1) Sural nerve (1) Ultrastructure (1) Wallerian degeneration (1) Watery degeneration (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 2001 (1) 2000 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Watery and dark axons in Wallerian degeneration of the opossum's optic nerve: different patterns of cytoskeletal breakdown? Anais da ABC (AABC) NARCISO,MARCELO S.; HOKOÇ,JAN NORA; MARTINEZ,ANA M. B.. In this paper we report a qualitative morphological analysis of Wallerian degeneration in a marsupial. Right optic nerves of opossums Didelphis marsupialis were crushed with a fine forceps and after 24, 48, 72, 96 and 168 hours the animals were anaesthetized and perfused with fixative. The optic nerves were immersed in fixative and processed for routine transmission electron microscopy. Among the early alterations typical of axonal degeneration, we observed nerve fibers with focal degeneration of the axoplasmic cytoskeleton, watery degeneration and dark degeneration, the latter being prevalent at 168 hours after crush. Our results point to a gradual disintegration of the axoplasmic cytoskeleton, opposed to the previous view of an "all-or-nothing'' process... Tipo: Info:eu-repo/semantics/article Palavras-chave: Ultrastructure; Nerve fiber; Crush lesion; Watery degeneration; Dark degeneration; Marsupial. Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652001000200008 Early myelin breakdown following sural nerve crush: a freeze-fracture study BJMBR Martinez,A.M.B.; Canavarro,S.. In this study we describe the early changes of the myelin sheath following surgical nerve crush. We used the freeze-fracture technique to better evaluate myelin alterations during an early stage of Wallerian degeneration. Rat sural nerves were experimentally crushed and animals were sacrificed by transcardiac perfusion 30 h after surgery. Segments of the nerves were processed for routine transmission electron microscopy and freeze-fracture techniques. Our results show that 30 h after the lesion there was asynchrony in the pattern of Wallerian degeneration, with different nerve fibers exhibiting variable degrees of axon disruption. This was observed by both techniques. Careful examination of several replicas revealed early changes in myelin membranes... Tipo: Info:eu-repo/semantics/other Palavras-chave: Myelin breakdown; Wallerian degeneration; Freeze-fracture; Crush lesion; Sural nerve. Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000001200012 Registros recuperados: 2 Primeira ... 1 ... Última

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