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| Registros recuperados: 22 | |
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| Bava,Amadeo Javier; Trombetta,Luis; Galache,Viviana; Zuliani,María Victoria; Troncoso,Alcides. |
| Se realizó el diagnóstico de criptococosis en un paciente con lesiones cutáneas de aspecto moluscoide, presentes en gran número en el rostro, sospechadas clínicamente de ser provocadas por Histoplasma capsulatum. El paciente, posteriormente diagnosticado como VIH positivo, presentó además Cryptococcus neoformans en el LCR y fue tratado con anfotericina B endovenosa. Con material obtenido por escarificación de las lesiones se realizaron extendidos y practicaron cultivos. Aplicadas a los extendidos, las coloraciones de Giemsa, Grocott y mucicarmín de Mayer, permitieron la observación de levaduras redondas y capsuladas que en los cultivos en agar semillas de girasol desarrollaron colonias de color pardo que correspondieron a Cryptococcus neoformans. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cryptococcus neoformans; Criptococosis cutánea; Mucicarmín de Mayer. |
| Ano: 2010 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0325-29572010000100005 |
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| Colombo,G.; Táparo,C.V.; Araújo Júnior,E.C.; Makatu,M.Y.; Santos,F.S.; Marinho,M.. |
| Os pombos possuem uma rica diversidade de microrganismo, entre eles fungos sapróbios, como do gênero Cryptococcus, que podem atuar como agentes patogênicos para o homem e animais. Objetivou-se o isolamento, a caracterização bioquímica e a molecular de amostras de Cryptococcus spp. de excretas ambientas de pombos. Foram colhidas 100 amostras ambientais de pontos equidistantes e representativos da área da cidade de Araçatuba, São Paulo. As amostras foram rasteladas do solo de vias públicas, armazenadas em frasco coletor e encaminhadas para o Laboratório de Bacteriologia e Micologia da FMVA, onde foram processadas e cultivadas em duplicata, em placas de Petri contendo ágar Sabouraud dextrose a 4% e Niger. Em seguida, foram incubadas à temperatura ambiente e a... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cryptococcus neoformans; Pombos; Bioquímico; PCR; Saúde pública. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352015000601639 |
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| Li,Meng; Liao,Yong; Chen,Min; Pan,Weihua; Weng,Lixing. |
| Cryptococcus spp. are common causes of mycoses in immunocompromised patients. To determine the drug susceptibilities of clinical Cryptococcus spp. isolates, the characteristics of 61 clinical Cryptococcus spp. complex isolates and their antifungal susceptibilities were investigated, including 52 C. neoformans and 9 C. gattii isolates collected at Shanghai between 1993 and 2009. Antifungal susceptibility of clinical isolates to amphotericin B, fluconazole, itraconazole, and flucytosine were determined by the microdilution method M27-A2 and the ATB FUNGUS 3 kit. The 90% minimum inhibitory concentration (MIC90) and susceptibility ranges were as follows: 1 (0.0625-1) µg/mL for amphotericin B, 4 (0.125-16) µg/ mL for fluconazole, 0.25 (0.0313-4) µg/mL for... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cryptococcus neoformans; Cryptococcus gattii; Antifungal agents. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000200012 |
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| Adiwardana,Natanael Sutikno; Morás,Juliana de Angelo; Bernardo,Leandro Lombo; Klautau,Giselle Burlamaqui; Queiroz,Wladimir; Vidal,Jose Ernesto. |
| ABSTRACT Osteomyelitis due to Cryptococcus neoformans are described in mostly 10% of patients with disseminated cryptococcosis, being direct inoculation even more uncommon. We report the case of an HIV-infected patient with history of recurring itching on his scalp and repetitive local trauma. For eighteen months, he noticed a painful and slow growing lump on his scalp. He was submitted to an excisional biopsy of the lesion but no etiological diagnosis was identified. After this procedure, the post-surgical wound never completely healed. At admission, the patient presented nausea and headache for three days and an open orifice into his skull. Investigations confirmed meningitis and skull osteomyelitis caused by Cryptococcus neoformans. He was treated with... |
| Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Cryptococcus neoformans; Osteomyelitis; Skull; HIV. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000600499 |
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| Bollela,V.R.; Frigieri,G.; Vilar,F.C.; Spavieri Jr,D.L.; Tallarico,F.J.; Tallarico,G.M.; Andrade,R.A.P.; de Haes,T.M.; Takayanagui,O.M.; Catai,A.M.; Mascarenhas,S.. |
| Mortality and adverse neurologic sequelae from HIV-associated cryptococcal meningitis (HIV-CM) remains high due to raised intracranial pressure (ICP) complications. Cerebrospinal fluid (CSF) high opening pressure occurs in more than 50% of HIV-CM patients. Repeated lumbar puncture with CSF drainage and external lumbar drainage might be required in the management of these patients. Usually, there is a high grade of uncertainty and the basis for clinical decisions regarding ICP hypertension tends to be from clinical findings (headache, nausea and vomiting), a low Glasgow coma scale score, and/or fundoscopic papilledema. Significant neurological decline can occur if elevated CSF pressures are inadequately managed. Various treatment strategies to address... |
| Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Brain diseases; Intracranial hypertension; AIDS-related opportunistic infections; Cryptococcus neoformans; Monitoring. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000900501 |
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| Medeiros,C.S.; Pontes-Filho,N.T.; Camara,C.A.; Lima-Filho,J.V.; Oliveira,P.C.; Lemos,S.A.; Leal,A.F.G.; Brandão,J.O.C.; Neves,R.P.. |
| The in vivo antifungal activity of the naphthoquinone beta-lapachone against disseminated infection by Cryptococcus neoformans was investigated. Swiss mice were immunosuppressed daily with dexamethasone (0.5 mg per mouse) intraperitoneally for 3 days, the procedure was repeated 4 days later, and the animals were then challenged intravenously with C. neoformans (10(6) CFU/mL) 1 week later. Seven days after infection, the mice were divided into groups and treated daily with beta-lapachone (10 mg/kg, iv) for 7 (N = 6) and 14 days (N = 10). Amphotericin B (0.5 mg/kg) was used as comparator drug and an additional group received PBS. Treatment with beta-lapachone cleared the yeast from the spleen and liver, and the fungal burden decreased approximately 10(4)... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Beta-lapachone; Cryptococcus neoformans; Cryptococcosis; Immunesuppression; Experimental infection; Amphotericin B. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000400004 |
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| Horta,Jorge A; Faganello,Josiane; Rosa e Silva,Lívia K; Oliveira,Loiva T; Santurio,Jânio M; Vainstein,Marilene H; Alves,Sydney Hartz. |
| In this work we studied the susceptibility to heat and antifungal agents of the first strains of environmental Cryptococcus neoformans var neoformans (serotype D) isolated in the state of Rio Grande do Sul, Brazil. In order to achieve a rigorous analysis, we employed the methodology recommended by NCCLS, Yeast Nitrogen Base (YNB) proposed by Ghannoum et al (YNB-1), Antibiotic medium 3 (AM3) indicated by others, YNB adjusted to the NCCLS methodology (YNB-2) and Etest. Our results indicate that all strains were susceptible to amphotericin B (0.0625-0.5 µg/mL), fluconazole (0.125-8.0 µg/mL), itraconazole (0.031-0.25 µg/mL) and flucytosine (0.125-4.0 µg/mL). The C. neoformans serotype D strains were more susceptible to heat (47ºC/30 min) than C. neoformans... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cryptococcus neoformans; Heat susceptibility; Antifungal agents. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822005000100001 |
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| Oliveira,Luís Flávio Souza de; Fuentefria,Alexandre Meneghello; Klein,Fernanda da Silva; Machado,Michel Mansur. |
| In the last times, focus on plant research has increased all over the world. Euphorbia tirucalli L., a plant known popularly as Aveloz, and originally used in Africa, has been drawing attention for its use in the United States and Latin America, both for use as an ornamental plant and as a medicinal plant. E. tirucalli L. is a member of the family Euphorbiaceae and contains many diterpenoids and triterpenoids, in particular phorbol esters, apparently the main constituent of this plant, which are assumed to be responsible for their activities in vivo and in vitro. The in vitro antifungal activities of Euphorbia tirucalli (L.) against opportunistic yeasts were studied using microbroth dilution assay. The results showed that aqueous extract and latex... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Euphorbia tirucalli L.; Aveloz; Antifungal; Cryptococcus neoformans. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000400027 |
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| Gutch,Ruchi Sethi; Nawange,Shesh Rao; Singh,Shankar Mohan; Yadu,Ruchika; Tiwari,Aditi; Gumasta,Richa; Kavishwar,Arvind. |
| In this study, we present antifungal susceptibility data of clinical and environmental isolates of Central Indian Cryptococcus neoformans (Serotype A, n = 8 and n = 50 respectively) and Cryptococcus gattii (Serotype B, n = 01 and n = 04 respectively). Susceptibilities to fluconazole, itraconazole and ketoconazole were determined by using NCCLS broth micro-dilution methodology. The total number of resistant strains for fluconazole in case of C. neoformans and C. gattii showed a significant difference by using chi-square test (p < 0.05*), while considering fisher's exact p value was nonsignificant (p > 0.05). However, the total number of resistant strains for itraconazole and ketoconazole was not found statistically significant. A comparison of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cryptococcus neoformans; Cryptococcus gattii; Minimum inhibitory concentration; Azoles; Central India. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000401125 |
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| Alves,Sydney Hartz; Oliveira,Loiva T.; Goulart,Letícia S.; Linares,Carlos Eduardo B.; Griebeler,Josiane; Santurio,Janio M.. |
| This study compared the performance of three culture media used for the determination of minimal inhibitory concentration (MIC) of amphotericin B and fluconazole against 48 Cryptococcus neoformans strains. For amphotericin B the media employed were RPMI 1640 medium, as indicated by NCCLS as reference, Yeast Nitrogen Base (YNB) as proposed by Ghannoum et al. (YNB-1), Antibiotic medium 3 (AM3) indicated by others, and YNB as proposed by us (YNB-2). In YNB-1, amphotericin B showed broader MIC ranges, varying from 0.125 µg/ml to 1.0 µg/ml; in RPMI 1640 medium and YNB-2 the MICs were similar and in AM3 the MIC ranges were narrower. The same pattern was observed for MIC 90%. For fluconazole the media employed were RPMI 1640 and YNB-1. The MIC ranges were broader... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cryptococcus neoformans; Susceptibility; Antifungal agents. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822002000100005 |
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| Guimarães,Geovani Pereira; Reis,Mysrayn Yargo de Freitas Araújo; Silva,Dayanne Tomaz Casimiro da; Mendonça Junior,Francisco Jaime Bezerra; Converti,Attílio; Pessoa Jr,Adalberto; Damasceno,Bolívar Ponciano Goulart de Lima; Silva,José Alexsandro da. |
| Fungal infections have become a major problem of worldwide concern. Yeasts belonging to the Candida genus and the pathogenic fungus Cryptococcus neoformans are responsible for different clinical manifestations, especially in immunocompromised patients. Antifungal therapies are currently based on a few chemotherapeutic agents that have problems related to effectiveness and resistance profiles. Microemulsions are isotropic, thermodynamically stable transparent systems of oil, water and surfactant that can improve the solubilization of lipophilic drugs. Taking into account the need for more effective and less toxic drugs along with the potential of thiophene derivatives as inhibitors of pathogenic fungi growth, this study aimed to evaluate the antifungal... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antifungal susceptibility; Cryptococcus neoformans; Microemulsion; Thiophene derivatives. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000200024 |
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| Registros recuperados: 22 | |
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