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| SOTO,CAROLINA R; ARROYO,JORGE; ALCAYAGA,JULIO. |
| Acetylcholine (ACh), adenosine 5'-triphosphate (ATP) and sodium cyanide (NaCN) activate petrosal ganglion (PG) neurons in vitro, and evoke ventilatory reflexes in situ, which are abolished after bilateral chemosensory denervation. Because in our previous experiments we superfused the isolated PG with solutions free of CO2 /HCO3¯ buffer, we studied its effects on the PG responses evoked in vitro. PGs from adult cats were superfused at a constant pH, with HEPES-supplemented (5 mM) saline with or without CO2 /HCO3¯ (5% / 26.2 mM) buffer, and carotid (sinus) nerve frequency discharge (CN) recorded. Increases in CN evoked by ACh, ATP and NaCN in CO2-free saline were significantly reduced (P<0.05, Wilcoxon test) when CO2 / HCO3¯ was present in the... |
| Tipo: Journal article |
Palavras-chave: Petrosal Ganglion; Carotid sinus nerve; Carbon dioxide; Bicarbonate; Acetylcholine; Adenosine 5'- triphosphate; Cyanide. |
| Ano: 2002 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000300010 |
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| Rufino,Marcos Natal; Cereda,Marney Pascoli; Barreto,Wanessa Teixeira Gomes; Silva,Alanderson Rodrigues da; Andrade,Gisele Braziliano de; Herrera,Heitor Miraglia. |
| ABSTRACT Cassava has been widely used for animal and human nutrition. It has also been demonstrated to have antineoplastic and anthelmintic properties. Toxicity due to cassava consumption has been reported in ruminants and laboratory animals; therefore, this study aimed to investigate the toxic effects of acetone cyanohydrin, a metabolite of linamarin that is present in cassava, in Wistar rats. Six groups of five animals each were used to evaluate the toxic effects of acetone cyanohydrin administered at 25 (G1), 50 (G2), 75 (G3), 100 (G4) and 125 (G5) µmol/kg as a single oral dose. The control group received acidified water (pH 3.5). The animals were monitored after administration of acetone cyanohydrin, and clinical symptoms were recorded. Serum enzyme... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Neurotoxic; Hepatotoxic; Cyanide; Acute intoxication. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-70542016000500577 |
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| Fonseca,Raíza Cavalcante; Souza,Nayane Alves de; Correa,Tâmara Cristina Lima; Garcia,Luane Ferreira; Reis,Luann Guilherme Vieira dos; Rodriguez,Armando Garcia. |
| Artemia salina bioassay was used to assess toxicity of seeds and kernels of Brazilian fruits from cerrado (central high plains region) and other inner regions of the country. Water extracts of the kernels were filtered and added to Artemia cultures containing ten individuals per mL. Dose - response curves were constructed, and LD50 values were calculated. Pure potassium cyanide standard was used to draw a calibration curve for comparison to detect the presence of cyanide in the samples tested. Extracts of the seeds of araticum, mangaba, cagaita, jatobá, and tucumã were found toxic to Artemia salina, and some of the dose - response curves were very similar in shape to those obtained with pure potassium cyanide standards, while the samples of baru,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cyanide; Kernels; Food toxicology. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612013000200006 |
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| Wobeto,Carmen; Corrêa,Angelita Duarte; Abreu,Celeste Maria Patto de; Santos,Custódio Donizete dos; Pereira,Henrique Victor. |
| In Brazil, the cassava leaf meal (CLM) has been used to strive against undernourishment because it is a high source of vitamins and minerals. However, the wide variation in the chemical composition of the different cultivars, as well as their antinutritional substances may be a restriction to their uses. The levels of some antinutrients in CLM from five cultivars at three ages of the plant (TAP) were investigated, in order to select the cultivars and plant ages that would be more appropriate for human consumption. The lowest contents of antinutrients were observed in the 12-month old plants, except for nitrate and hemagglutinin from which the lowest contents were found for the 17 month old ones. The cultivar IAC 289-70 had the lowest antinutrient levels,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cassava leaves; Cyanide; Polyphenol; Saponin; Hemagglutinin; Cultivars. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612007000100019 |
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| Oboh,Ganiyu. |
| Cassava pulp was fermented with pure strains of Saccharomyces cerevisae and two bacteria namely Lactobacillus delbruckii and Lactobacillus coryneformis for 3 days. The squeezed liquid from the fermented pulp was used to ferment cassava peels for 7 days. Analysis of the dried fermented peels revealed that there was a significant (P < 0.05) increase in the protein content of the cassava peels fermented with squeezed liquid from the inoculated cassava pulp (21.5%) when compared with the unfermented cassava peel (8.2%). Moreover, the treatment equally brought about a significant (P < 0.05) decrease in the cyanide (6.2 mg/kg) and phytate content (789.7 mg/100g) when compared with the unfermented cassava peels, which had 44.6 mg/kg cyanide and 1043.6... |
| Tipo: Journal article |
Palavras-chave: Cassava peels; Cyanide; Fermentatio; Protein. |
| Ano: 2006 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582006000100007 |
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| CEREDA,M. P.; MATTOS,M.C.Y.. |
| Cassava is a widely grown root crop which accumulates two cyanogenic glucosides, linamarin and lotaustralin. Linamarin accounts for more than 80% of the cassava cyanogenic glucosides. It is a ß-glucoside of acetone cyanohydrin and ethyl-methyl-ketone-cyanohydrin. Linamarin ß-linkage can only be broken under high pressure, high temperature and use of mineral acids, while its enzymatic break occurs easily. Linamarase, an endogenous cassava enzyme, can break this ß-linkage. The enzymatic reaction occurs under optimum conditions at 25ºC, at pH 5.5 to 6.0. Linamarin is present in all parts of the cassava plant, being more concentrated on the root and leaves. If the enzyme and substrate are joined, a good detoxification can occur. All the cassava plant species... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cyanide; Cassava; Linamarin; Cyanogenic glucoside; Residues; Waste water; Culinary and industrial uses. |
| Ano: 1996 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301996000100002 |
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| FIPKE,M.V.; VIDAL,R.A.. |
| ABSTRACT Quinclorac is a systemic herbicide absorbed by germinating seeds, roots and leaves of seedlings. It is a selective compound for crops such as rice, canola, barley, corn, sorghum, and pasture. Quinclorac can be used to control various monocots and dicotyledonous weed species. The biochemical function of this herbicide in the plant has intrigued scientists for nearly four decades. The objectives of this review are to present evidence of three hypotheses on the biochemical functioning of quinclorac and to propose an integrative mode of action. The first theory on the mode of action of quinclorac is supported by evidence of inhibition of incorporation of C14-glucose into cellulose and hemicellulose, thus, affecting the cell wall synthesis. The second... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cellulose biosynthesis-inhibitor; Cyanide; Auxinic herbicide; Reactive oxygen species. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-83582016000200393 |
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