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| Mohamad,Nora; Gutiérrez,Alicia; Núñez,Mariel; Cocca,Claudia; Martín,Gabriela; Cricco,Graciela; Medina,Vanina; Rivera,Elena; Bergoc,Rosa. |
| Apoptosis or programmed cell death (PCD) is a physiological process characteristic of pluricellular organisms leading to self-destruction of the cell. It is therefore involved in development, homeostasis and host defense. However, a significant difference has been shown between mammalian cell apoptosis and non-mammalian cell apoptosis: mitochondria are implicated only in the former. Execution of PCD includes the release of several proapoptotic proteins from the intermembrane space of mitochondria. They could exert their actions through a caspase dependent as well as a caspase independent way. On the other hand, regulation of PCD is mainly given by the Bcl-2 family members, which are in turn essentially regulated by activation of death receptors and/or DNA... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Apoptosis; Mitochondria; Bcl-2 family; Cytochrome-c. |
| Ano: 2005 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452005000200001 |
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