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	Provedor de dados 42 (2) 56 (1) 60 (1) 74 (1) Autor ALPAY,MERVE (1) Asgharzade,Samira (1) Carvalho,José Carlos Tavares (1) Cascon,Vera (1) DULGER,BASARAN (1) DULGER,GORKEM (1) Dolabela,M.F. (1) Kaplan,Maria Auxiliadora Coelho (1) Lopes,M.T.P. (1) Maistro,Edson Luis (1) Nelson,D.L. (1) Nikoo,Mehdi (1) Pereira,M.T. (1) Piló-Veloso,D. (1) Rabiei,Sana (1) Rafieia-kopai,Mahmoud (1) Rezaei,Masoud (1) SAHIN,IBRAHIM E. (1) Salas,C.E. (1) Silva,Pâmela S. (1) Mais... Palavra-chave Cytotoxic effect (5) Antioxidant activity (2) Aminothiols (1) Antimicrobial activity (1) Antitumorigenic effect (1) Aqueous extract (1) Chromosome aberrations (1) Copaifera duckei (Caesalpinaceae) (1) Cybopogon citratus (1) Endemic plant (1) Genotoxic effect (1) Lactuca sativa (1) Liza klunzingeri (1) Micronucleus test (1) Phlomis russeliana (1) Phytochemical characterization (1) Protein hydrolysate (1) Radioprotector (1) Mais... Tipo do documento Info:eu-repo/semantics/article (4) Info:eu-repo/semantics/other (1) Ano 2019 (2) 2010 (1) 2005 (1) 1998 (1) País Brazil (5) Idioma Inglês (5)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 5 Primeira ... 1 ... Última Cytogenotoxicity of Cymbopogon citratus (DC) Stapf (lemon grass) aqueous extracts in vegetal test systems 42 Sousa,Saulo M.; Silva,Pâmela S.; Viccini,Lyderson F.. The lemon grass, Cymbopogon citratus (DC) Stapf, is an important species of Poaceae family commonly used in the folk medicine in many countries. The aim of this study was to investigate the cytotoxic and genotoxic effects of aqueous extracts from C. citratus leaves on Lactuca sativa (lettuce) root tip meristem cells by cytogenetic studies that have never been done before for lemon grass extracts. For this, lettuce seeds were treated for 72h with different concentrations of lemon grass aqueous extracts (5; 10; 20 and 30 mg/mL). The percentage of germination, root development and cellular behavior were analyzed, and the results showed that the highest concentration of aqueous extracts reduced the mitotic index, the seed germination and the root development... Tipo: Info:eu-repo/semantics/article Palavras-chave: Aqueous extract; Cybopogon citratus; Cytotoxic effect; Genotoxic effect; Lactuca sativa. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652010000200006 Evaluating antimicrobial and antioxidant capacity of endemic Phlomis russeliana from Turkey and its antiproliferative effect on Human Caco-2 Cell Lines 42 ALPAY,MERVE; DULGER,GORKEM; SAHIN,IBRAHIM E.; DULGER,BASARAN. Abstract: In this study, the antimicrobial, antioxidant and antitumor activity of ethanol extracts obtained from Phlomis russeliana (Sims.) Lag. ex Benth. (Lamiaceae) were evaluated. Disc diffusion and microdilution methods were used to test the extracts for antimicrobial activity against seven bacteria strains (Bacillus cereusATCC 7064, Bacillus subtilisATCC 6633, Staphylococcus aureusATCC 6538P, Escherichia coliATCC 10538, Proteus vulgarisATCC 6899, Salmonella typhimuriumCCM 5445 and Pseudomonas aeruginosaATCC 27853) and four yeast strains (Kluyveromyces fragilisATCC 8608, Rhodotorula rubraATCC 70403, Debaryomyces hanseniiDSM 70238 and Candida albicansATCC 10239). Notably, they were more effective against the yeast strains than the bacterial strains. Of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Phlomis russeliana; Antioxidant activity; Cytotoxic effect; Antimicrobial activity; Endemic plant. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000500604 The radioprotective effect of a new aminothiol (20-PRA) 56 Dolabela,M.F.; Pereira,M.T.; Salas,C.E.; Steffani,G.M.; Nelson,D.L.; Piló-Veloso,D.; Lopes,M.T.P.. We examined the radioprotective effect of aminothiol 2-N-propylamine-cyclo-hexanethiol (20-PRA) on a human leukemic cell line (K562) following various radiation doses (5, 7.5 and 20 Gy) using a source of 60Co <FONT FACE="Symbol">g</FONT>-rays. At 5 Gy and 1 nM 20-PRA, a substantial protective effect (58%) was seen 24 h after irradiation, followed by a decrease at 48 h (11%). At the high radiation dose (20 Gy) a low protective effect was also seen (35%). In addition, the antitumorigenic potential of 10 nM 20-PRA was shown by the inhibition of crown gall formation induced by Agrobacterium tumefaciens. The radioprotective potency of 20-PRA is 105-106 times higher than that of the aminothiol WR-1065 (N-(2-mercaptoethyl)-1,3-diaminopropane) whose... Tipo: Info:eu-repo/semantics/other Palavras-chave: Aminothiols; Cytotoxic effect; Radioprotector; Antitumorigenic effect. Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000800010 Antioxidant and cytotoxic properties of protein hydrolysates obtained from enzymatic hydrolysis of Klunzinger’s mullet (Liza klunzingeri) muscle 60 Rabiei,Sana; Rezaei,Masoud; Asgharzade,Samira; Nikoo,Mehdi; Rafieia-kopai,Mahmoud. Today, consumers are looking for functional foods that promote health and prevent certain diseases in addition to provide nutritional requirements. This study aimed to evaluate the antioxidant and cytotoxic properties of Liza klunzingeri protein hydrolysates. Fish protein hydrolysates (FPHs) were prepared from L. klunzingeri muscle using enzymatic hydrolysis with papain at enzyme/substrate ratios of 1:25 and 1:50 for 45, 90 and 180 min. The antioxidant activities of the FPHs were investigated through five antioxidant assays. The cytotoxic effects on 4T1 carcinoma cell line were also evaluated. The amino acid composition and molecular weight distribution of the hydrolysate with the highest antioxidant activity were determined by HPLC. All six FPHs exhibited... Tipo: Info:eu-repo/semantics/article Palavras-chave: Antioxidant activity; Cytotoxic effect; Protein hydrolysate; Liza klunzingeri. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100569 In vivo evaluation of the mutagenic potential and phytochemical characterization of oleoresin from Copaifera duckei Dwyer 74 Maistro,Edson Luis; Carvalho,José Carlos Tavares; Cascon,Vera; Kaplan,Maria Auxiliadora Coelho. We characterized the chemical constituents of Copaifera duckei oleoresin and used dermal application to Wistar rats to evaluated its possible mutagenic and cytotoxic activities on peripheral blood reticulocytes and bone marrow cells. Chemical characterization of the oleoresin revealed the presence of sesquiterpene hydrocarbons, an unidentified neutral diterpene and diterpene acids. To evaluate mutagenicity evaluation the rats were treated with 10, 25 and 50% of the LD50 dose of the oleoresin for three consecutive days and peripheral blood collected after 0, 24, 48 and 72 h for micronucleus analysis. The rats were humanly sacrificed 24 hours after the last treatment and chromosome preparations made using standard techniques. At the three concentrations and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Copaifera duckei (Caesalpinaceae); Phytochemical characterization; Micronucleus test; Chromosome aberrations; Cytotoxic effect. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000500028 Registros recuperados: 5 Primeira ... 1 ... Última

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