Sabiia Seb
PortuguêsEspañolEnglish
Embrapa
        Busca avançada

Botão Atualizar


Botão Atualizar

Ordenar por: 

RelevânciaAutorTítuloAnoImprime registros no formato resumido
Registros recuperados: 2
Primeira ... 1 ... Última
Imagem não selecionada

Imprime registro no formato completo
Regulation of adipogenesis by nucelar receptor PPARγ is modulated by the histone demethylase JMJD2C Genet. Mol. Biol.
Fernando,Lizcano; Carolina,Romero; Vargas,Diana.
A potential strategy to combat obesity and its associated complications involves modifying gene expression in adipose cells to reduce lipid accumulation. The nuclear receptor Peroxisome Proliferator-activated receptor gamma (PPARγ) is the master regulator of adipose cell differentiation and its functional activation is currently used as a therapeutic approach for Diabetes Mellitus type 2. However, total activation of PPARγ induces undesirable secondary effects that might be set with a partial activation. A group of proteins that produce histone demethylation has been shown to modify the transcriptional activity of nuclear receptors. Here we describe the repressive action of the jumonji domain containing 2C/lysine demethylase 4 C (JMJD2C/KDM4C) on PPARγ...
Tipo: Info:eu-repo/semantics/article Palavras-chave: PPARγ; Histones; Demethylation; JMJD2C; Deacetylation; Adipocyte; Trichostatin A.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000100004
Imagem não selecionada

Imprime registro no formato completo
A Michaelis–Menten type equation for describing methylmercury dependence on inorganic mercury in aquatic sediments ArchiMer
Cossa, Daniel; Garnier, Cedric; Buscail, Roselyne; Elbaz-poulichet, Francoise; Mikac, Nevenka; Patel-sorrentino, Nathalie; Tessier, Erwan; Rigaud, Sylvain; Lenoble, Veronique; Gobeil, Charles.
Methylation of mercury (Hg) is the crucial process that controls Hg biomagnification along the aquatic food chains. Aquatic sediments are of particular interest because they constitute an essential reservoir where inorganic divalent Hg (HgII) is methylated. Methylmercury (MeHg) concentrations in sediments mainly result from the balance between methylation and demethylation reactions, two opposite natural processes primarily mediated by aquatic microorganisms. Thus, Hg availability and the activity of methylating microbial communities control the MeHg abundance in sediments. Consistently, some studies have reported a significant positive correlation between MeHg and HgII or total Hg (HgT), taken as a proxy for HgII, in aquatic sediments using...
Tipo: Text Palavras-chave: Mercury; Methylmercury; Aquatic sediment; Methylation; Demethylation.
Ano: 2014 URL: http://archimer.ifremer.fr/doc/00171/28220/26520.pdf
Registros recuperados: 2
Primeira ... 1 ... Última
 

Empresa Brasileira de Pesquisa Agropecuária - Embrapa
Todos os direitos reservados, conforme Lei n° 9.610
Política de Privacidade
Área restrita

Embrapa
Parque Estação Biológica - PqEB s/n°
Brasília, DF - Brasil - CEP 70770-901
Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco

Valid HTML 4.01 Transitional