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Histological and immunohistochemical evaluation of two cell therapy protocols in equine suspensory ligament repair Arq. Bras. Med. Vet. Zootec.
Garbin,L.C.; Soares,A.S.; Mendes,H.M.F.; Cassali,G.D.; Vasconcelos,A.C.; Faleiros,R.R..
ABSTRACT This study aimed to histologically evaluate the quality of tissue repair in equine suspensory ligament treated with two cell therapy protocols. All four limbs of six animals were operated simultaneously to remove a fragment in each ligament using a skin biopsy punch. Two days later, intralesional injections were performed using bone marrow mononuclear fraction (BM group), cultivated cells derived from adipose tissue (AT group), saline (positive control group), or no treatment (negative control group), in such way that each horse received all treatments. After sixty days biopsies were performed for histological analysis (H & E, Masson’s trichrome and picrosirius red) and immunohistochemistry analysis (collagen type III). Histological findings...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Stem cell therapy; Desmitis; Hors.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000501469
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