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On-line analysis of biosignals for the automation of total and specific sleep deprivation in the rat Biol. Res.
VIVALDI,ENNIO A; BASSI,ALEJANDRO; ESTRADA,JORGE; GARRIDO,IGNACIO; DÍAZ,JAVIER; OCAMPO-GARCÉS,ADRIÁN.
A computer-based system that automates sleep studies, including sleep deprivation paradigms, is described. The system allows for total or REM-specific sleep deprivation and is based on a reliable, fast-responding, on-line state detection algorithm linked to a dependable intervention device. Behavioral state detection is achieved by dimensión reduction of short-term EEG power spectrum. Interventions are made by serial outputs to servomotors that move a cage with different patterns and variable intensity. The system can adapt itself to individual characteristics and to changes in recording conditions. Customized protocols can be designed by defining the states or stages to be deprived, including scheduling temporal patterns. A detailed analysis of the...
Tipo: Journal article Palavras-chave: Sleep; Sleep deprivation; Biosignal analysis; Digital control; Automation.
Ano: 2008 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000400009
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