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Sawtooth waves during REM sleep after administration of haloperidol combined with total sleep deprivation in healthy young subjects BJMBR
Pinto Jr.,L.R.; Peres,C.A.; Russo,R.H.; Remesar-Lopez,A.J.; Tufik,S..
We sought to examine the possible participation of dopaminergic receptors in the phasic events that occur during rapid eye movement (REM) sleep, known as sawtooth waves (STW). These phasic phenomena of REM sleep exhibit a unique morphology and, although they represent a characteristic feature of REM sleep, little is known about the mechanisms which generate them and which are apparently different from rapid eye movements. STW behavior was studied in 10 male volunteers aged 20 to 35 years, who were submitted to polysomnographic monitoring (PSG). On the adaptation night they were submitted to the first PSG and on the second night, to the basal PSG. On the third night the volunteers received placebo or haloperidol and spent the whole night awake. On the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sawtooth waves; REM sleep; Sleep deprivation; Dopaminergic receptors; Rapid eye movements; Haloperidol.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000500013
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