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	Provedor de dados BJPS (1) International Journal of Morphology (1) Autor Collett,John H (1) Couto,Renê Oliveira do (1) Issa,João Paulo Mardegan (1) Jensen,Carlos Eduardo de Matos (1) Lara,Elza Helena Guimarães (1) Panzeri,Heitor (1) Pedrazzi,Vinícius (1) Rodrigues,Deborah Fernandes (1) Sinisterra,Rubén Dario (1) Mais... Palavra-chave Drug delivery systems (2) Dissolution (1) Fluoride (1) Mucin (1) Nanoparticles (1) Oral delivery (1) Oral mucosa (1) Poly-methylmethacrylate (1) Simvastatin (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Journal article (1) Ano 2020 (1) 2009 (1) País Brazil (1) Chile (1) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última In vitro Fluoride Release and Tensile Bond Strength of a Polymeric Intra-Buccal Bioadhesive International Journal of Morphology Pedrazzi,Vinícius; Lara,Elza Helena Guimarães; Panzeri,Heitor; Collett,John H; Issa,João Paulo Mardegan. The intra-buccal polymeric bioadhesive systems that can stay adhered to the oral soft tissues for drug programmed release, with the preventive and/or therapeutic purpose has been employed for large clinical situations. A system based on hydroxypropyl methyl cellulose/Carbopol 934'/magnesium stearate (HPMC/Cp/StMg) was developed having the sodium fluoride as active principle. This kind of system was evaluated according to its resistance to the removal by means of physical test of tensile strength. Swine buccal mucosa extracted immediately after animals' sacrifice was employed as substrate for the physical trials, to obtain 16 test bodies. Artificial saliva with or without mucin was used to involve the substrate/bioadhesive system sets during the trials.... Tipo: Journal article Palavras-chave: Drug delivery systems; Oral delivery; Mucin; Oral mucosa; Fluoride. Ano: 2009 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000300026 Novel Eudragit® -based polymeric nanoparticles for sustained release of simvastatin BJPS Rodrigues,Deborah Fernandes; Couto,Renê Oliveira do; Sinisterra,Rubén Dario; Jensen,Carlos Eduardo de Matos. This paper reports on the development of nanoparticles aiming at the in vitro controlled release of simvastatin (SVT). The nanoparticles were prepared by the nanoprecipitation method with polymers Eudragit® FS30D (EDGFS) or Eudragit® NE30D (EDGNE). EDGFS+SVT nanoparticles showed mean size of 148.8 nm and entrapment efficiency of 76.4%, whereas EDGNE+SVT nanoparticles showed mean size of 105.0 nm and entrapment efficiency of 103.2%. Infrared absorption spectra demonstrated that SVT incorporated into the polymer matrix, especially EDGNE. Similarly, the differential scanning calorimeter (DSC) curve presented no endothermic peak of fusion, indicating that the system is amorphous and the drug is not in the crystalline state. The maintenance of SVT in the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Simvastatin; Nanoparticles; Poly-methylmethacrylate; Dissolution; Drug delivery systems. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100591 Registros recuperados: 2 Primeira ... 1 ... Última

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