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| Cardoso,K.C.F.; Ferreira,M.A.; Miguel,M.P.; Bolzan,A.A.; Nishimori,C.T.D.; Franco,L.G.; Honsho,C.S.. |
| The objective of this study was to evaluate the clinical and histological effects of occluding the nasolacrimal ducts and points of rabbits. For this study, 20 adult New Zealand rabbits, both males and females, weighing 3.2±0.4kg were allocated into two groups for n-butyl-cyanoacrylate occlusion (GB, n=10) or 2-octyl-cyanoacrylate occlusion (GO, n=10). The contralateral eyes served as the controls. The persistence of tears was evaluated daily using the Schirmer I test. Discomfort, eye discharge, epiphora, and conjunctival hyperemia were assessed prior to the procedure (T0) and during the 14 subsequent days (T1-T14). On days seven and 14, five animals from each group were euthanized, and their nasolacrimal ducts were collected, processed and analyzed by... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dry eye; Keratoconjunctivitis sicca; Schirmer test; Tear. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352013000600021 |
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| Traipe-Salas,Felipe; Traipe-Castro,Leonidas; Salinas-Toro,Daniela; López,Daniela; Valenzuela,Felipe; Cartes,Christian; Toledo-Araya,Héctor; Pérez,Claudio; Solís,Remigio López. |
| BACKGROUND: Tear desiccation on a glass surface followed by transmitted-light microscopy has served as diagnostic test for dry eye. Four distinctive morphological domains (zones I, II, III and transition band) have been recently recognized in tear microdesiccates. Physicochemical dissimilarities among those domains hamper comprehensive microscopic examination of tear microdesiccates. Optimal observation conditions of entire tear microdesiccates are now investigated. One-μ! aliquots of tear collected from individual healthy eyes were dried at ambient conditions on microscope slides. Tear microdesiccates were examined by combining low-magnification objective lenses with transmitted-light microscopy (brightfield, phase contrasts Ph1,2,3 and... |
| Tipo: Journal article |
Palavras-chave: Tear; Tear ferning test; Transmitted-light microscopy; Tear microdesiccate; Dry eye. |
| Ano: 2016 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602016000100028 |
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| Traipe-Castro,Leonidas; Salinas-Toro,Daniela; López,Daniela; Zanolli,Mario; Srur,Miguel; Valenzuela,Felipe; Cáceres,Aníbal; Toledo-Araya,Héctor; López-Solís,Remigio. |
| BACKGROUND: Fern-like crystalloids form when a microvolume of tear is allowed to dry out at ambient conditions on a glass surface. Presence of crystalloids in tear "microdesiccates" is used to evaluate patients with Dry-Eye disease. This study aims to examine morphologically the desiccation process of normal tear fluid and to identify changes associated with accelerated tear evaporation. Tear microdesiccates from healthy (Non-Dry Eye) and Dry Eye subjects were produced at ambient conditions. Microdesiccate formation was monitored continuously by dark-field video microscopy. Additionally, accelerated desiccation of tear samples from healthy subjects was conducted under controlled experimental conditions. Particular morphological domains of tear... |
| Tipo: Journal article |
Palavras-chave: Tear; Tear ferning test; Dry eye; Dark-field microscopy. |
| Ano: 2014 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100025 |
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