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| Registros recuperados: 22 | |
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| Calvo Arriaga, Ayne Oliva. |
| La diabetes mellitus afecta a más de 220 millones de personas en el mundo y es una de las causas principales de muerte. Existe evidencia de que los frutos ácidos de Opuntia joconostle y O. matudae, denominados xoconostle, disminuyen la glucemia e incrementan la concentración sérica de insulina en individuos diabéticos. El presente estudio fue propuesto para dilucidar si esos efectos y otros relacionados con el metabolismo energético, como la disminución de colesterol y triglicéridos en la sangre, se deben a los mucílagos, pectinas o hemicelulosas de xoconostle, a todos ellos o a ninguno de ellos. La hipótesis es que estos polisacáridos ocasionan disminución de las concentraciones séricas de glucosa, colesterol y triglicéridos, e incremento de la secreción... |
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Palavras-chave: Dislipidemia; Fibra alimentaria; Glucemia; Insulina; Dietary fiber; Dyslipidemia; Glycemia; Insulin; Maestría; Botánica. |
| Ano: 2011 |
URL: http://hdl.handle.net/10521/526 |
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| Calvo Arriaga, Ayne Oliva. |
| La diabetes mellitus afecta a más de 220 millones de personas en el mundo y es una de las causas principales de muerte. Existe evidencia de que los frutos ácidos de Opuntia joconostle y O. matudae, denominados xoconostle, disminuyen la glucemia e incrementan la concentración sérica de insulina en individuos diabéticos. El presente estudio fue propuesto para dilucidar si esos efectos y otros relacionados con el metabolismo energético, como la disminución de colesterol y triglicéridos en la sangre, se deben a los mucílagos, pectinas o hemicelulosas de xoconostle, a todos ellos o a ninguno de ellos. La hipótesis es que estos polisacáridos ocasionan disminución de las concentraciones séricas de glucosa, colesterol y triglicéridos, e incremento de la secreción... |
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Palavras-chave: Dislipidemia; Fibra alimentaria; Glucemia; Insulina; Dietary fiber; Dyslipidemia; Glycemia; Insulin; Maestría; Botánica. |
| Ano: 2011 |
URL: http://hdl.handle.net/10521/526 |
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| Lins,Tulio C.; Pires,Alause S.; Paula,Roberta S.; Moraes,Clayton F.; Vieira,Rodrigo G.; Vianna,Lucy G.; Nobrega,Otávio T.; Pereira,Rinaldo W.. |
| The prevalence of metabolic disorders varies among ethnic populations and these disorders represent a critical health care issue for elderly women. This study investigated the correlation between genetic ancestry and body composition, metabolic traits and clinical status in a sample of elderly women. Clinical, nutritional and anthropometric data were collected from 176 volunteers. Genetic ancestry was estimated using 23 ancestry-informative markers. Pearsons correlation test was used to examine the relationship between continuous variables and an independent samples t-test was used to compare the means of continuous traits within categorical variables. Overall ancestry was a combination of European (57.49%), Native American (25.78%) and African (16.73%).... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dyslipidemia; Genetic ancestry; Lipid profile; Obesity; Postmenopausal women. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000400005 |
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| Cavenaghi,F. M; Bataglion,C. A. N; Paula,P. C; Motta,A. C. F; Komesu,M. C. |
| Protease inhibitors (PIs), part of HAART (Highly Active Antiretroviral Therap) are selective, competitive inhibitors of protease, a crucial enzyme to viral maturation, infection and replication. A lipodystrophic syndrome has been reported in individuals treated with HAART, and associated to hyperglycemia, hypercholesterolemia, hypertrigliceridemia, hyperlipidemia, hypertension and hypreinsulinemia. The HAART-associated metabolic abnormalities were first associated with protease inhibitors, Ritonavir mostly, but the mechamisns that underlie these metabolic alterations are to date, not completely understood. Since PIs are candidate to be the drug of choice for other diseases treatment, such as the Hepatitis C, malaria and some types of cancer, it seems to be... |
| Tipo: Journal article |
Palavras-chave: Protease inhibitors; Dyslipidemia; Metabolic disorders. |
| Ano: 2012 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000200014 |
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| Pontes,L. C. R.; Carvalho,L. R.; Souza,L. R.; Trindade,E. B. S. M.; Pereira,P. C. M.. |
| Highly active antiretroviral therapy (HAART) has been associated with the development of a clinical group and metabolic disorders such as peripheral lipodystrophy syndrome in AIDS. The aim of this study was to analyze the lipid profile, the clinical aspects, and the body composition of HIV-1 infected individuals treated with or without protease inhibitor (PI) during the highly active antiretroviral therapy. In total, 62 individuals were evaluated in this study; 15 healthy individuals (Control Group: CG), 11 HIV-1 infected individuals treated without antiretroviral therapy (Group 1: G1), 14 HIV-1 infected individuals treated with antiretroviral therapy plus protease inhibitor (Group 2: G2), and 22 HIV-1 infected individuals treated with antiretroviral... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Lipodystrophy; HIV-1; Highly active antiretroviral therapy; Dyslipidemia; Hypertriglyceridemia. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992005000200006 |
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| Sarto,Danielle Aparecida Quintino Silva; Siqueira,Ana Helena D’Arcadia de; Magalhaes,Francisco Monteiro de Almeida; Caproni,Karine de Paula; Martins,Ângela Maria; Santos,Gérsika Bitencourt; Silva,Délcio Bueno da; Boas,Brígida Monteiro Vilas; Garcia,José Antônio Dias. |
| ABSTRACT The control of dyslipidemia by using herbal products is an important subject for studies. In this study, we evaluated the effects of dry Passiflora incarnata L. extract over dyslipidemia, left ventricular hypertrophy, and hepatic oxidative stress of LDL receptor knockout mice (LDLr-/-). Forty 4-month old male LDLr-/- mice were distributed into four groups: Group standard diet; Group standard diet and 200 mg/kg of body weight of Passiflora incarnata L. leaf dry extract; Group high-fat diet; Group high-fat diet and 200 mg/kg of body weight of Passiflora incarnata L. leaf dry extract. After 30 days, Passiflora incarnata L. dry extract reduced the effects of the high-fat diet, with a decrease of total cholesterol, triglycerides, and increase of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Passion fruit; Left ventricular hypertrophy; Dyslipidemia; Oxidative stress. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100321 |
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| Monnerat,Bruno Zanotelli; Cerutti Junior,Crispim; Caniçali,Sheila Cristina; Motta,Tânia Reuter. |
| We designed a retrospective cohort study to identify factors associated with HIV-1 related lipodystrophy at a tertiary HIV-care center in Vitória, ES, Brazil. Inclusion criteria were documented HIV diagnosis, anti-retroviral therapy and age above 17 years. Highly active antiretroviral therapy (HAART) was initially the exposure variable, but a second analysis was also performed, as a nested case-control, based on the presence or absence of lipodystrophy. Use of protease inhibitors (PI) was associated with an increase in serum triglycerides (243.7 ± 189 mg/dL vs. 172.7 ± 131 mg/dL, p = 0.015), but not of total cholesterol (TC) or HDL fraction levels. Non-nucleoside reverse transcriptase inhibitors (NNRTI) were associated with an increase in serum TC (180.6 ±... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Lipodystrophy; Dyslipidemia; Brazil; AIDS; ARV therapy; Cohort study. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000400002 |
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| Geraix,Juliana; Ardisson,Lidiane Paula; Marcondes-Machado,Jussara; Pereira,Paulo Câmara Marques. |
| Chagas disease (CD), caused by the protozoan Trypanossoma cruzi, affects approximately 18 million individuals in the Americas, 5 million of which live in Brazil. Most chronic sufferers have either the indeterminate form of the disease, without organic compromise, or the cardiac or digestive forms. Despite the importance of this disease, there is no information on the effect of nutrition on CD evolution. We evaluated the clinical-nutritional profile of individuals with CD treated at the Tropical Diseases Nutrition Out-Patient Clinic of the Botucatu School of Medicine, UNESP. A retrospective cohort study was performed between 2002 and 2006, on 66 patients with serum and parasitological diagnosis of CD. Epidemiological, clinical, nutritional, and biochemical... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Chagas disease; Nutrition; Dyslipidemia. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000400008 |
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| Papi,Luanda; Menezes,Ana Carolina G.B.; Rocha,Hélio; Abreu,Thalita F.; Oliveira,Ricardo Hugo de; Frota,Ana Cristina C.; Evangelista,Lucia de A.; Hofer,Cristina B.. |
| The aim of present study was to describe the frequency of lipodystrophy syndrome associated with HIV (LSHIV) and factors associated with dyslipidemia in Brazilian HIV infected children. HIV infected children on antiretroviral treatment were evaluated (nutritional assessment, physical examination, and laboratory tests) in this cross-sectional study. Univariate analysis was performed using Mann-Whitney test or Fisher's exact test followed by logistic regression analysis. Presence of dyslipidemia (fasting cholesterol >200 mg/dl or triglycerides >130 mg/dl) was the dependent variable. 90 children were enrolled. The mean age was 10.6 years (3-16 years), and 52 (58%) were female. LSHIV was detected in 46 children (51%). Factors independently associated... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HIV; Lipodystrophy; Dyslipidemia; Children. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000400394 |
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| Pinto Neto,Lauro Ferreira da Silva; Neves,Mariza Barros das; Ribeiro-Rodrigues,Rodrigo; Page,Kimberly; Miranda,Angelica Espinosa. |
| OBJECTIVE: To evaluate the cumulative incidence of dyslipidemia and fasting glucose impairment three years after initiating the first antiretroviral (ART) regimen and the association with the type of ART regimen in an AIDS outpatient clinic in Brazil. METHODS: Retrospective cohort of HIV-1 infected patients attending an outpatient HIV clinic in Vitoria, Brazil, between January/2010 and May/2011. Data, including blood pressure, dyslipidemia (high total cholesterol and low HDL-C), fasting glucose, and cardiovascular risk by Framingham Risk Score were abstracted from medical records from clinic visits six months prior and three years after starting ART. We assessed independent associated factors for dyslipidemia using multiple logistic regression. RESULTS:... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dyslipidemia; Fasting glucose; AIDS; ART; Co-morbidity. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000400009 |
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| Cahn,P; Leite,O; Rosales,A; Cabello,R; Alvarez,CA; Seas,C; Carcamo,C; Cure-Bolt,N; L'Italien,Gp; Mantilla,P; Deibis,L; Zala,C; Suffert,T. |
| OBJECTIVE: Determine the prevalence of metabolic abnormalities (MA) and estimate the 10-year risk for cardiovascular disease (CVD) among Latin American HIV-infected patients receiving highly active anti-retroviral therapy (HAART). METHODS: A cohort study to evaluate MA and treatment practices to reduce CVD has been conducted in seven Latin American countries. Adult HIV-infected patients with at least one month of HAART were enrolled. Baseline data are presented in this analysis. RESULTS: A total of 4,010 patients were enrolled. Mean age (SD) was 41.9 (10) years; median duration of HAART was 35 (IQR: 10-51) months, 44% received protease inhibitors. The prevalence of dyslipidemia and metabolic syndrome was 80.2% and 20.2%, respectively. The overall 10-year... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HAART; HIV; Metabolic parameters; Cardiovascular risk factors; Metabolic syndrome; Dyslipidemia. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000200008 |
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| Zaid,M.; Hasnain,S.. |
| Previous studies have reported increased prevalence of coronary heart disease (CHD) in Indians and South Asian settlers in North America. This increased burden of CHD among South Asians is mainly caused by dyslipidemia. To the best of our knowledge, none of the previous works has studied the patterns and prevalence of dyslipidemia in the Pakistani population. The present work aimed to study the plasma lipid trends and abnormalities in a population-based sample of urban and rural Pakistanis. The study included 238 participants (108 males,130 females). Plasma lipid profiles of the participants were determined using standard protocols. We observed that 63% of the study population displayed irregularities in at least one major lipid-fraction including total... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Plasma Lipids; Dyslipidemia; Coronary heart disease. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000900609 |
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| Li,Zhao; Wu,Ying-Ying; Yu,Bei-Xin. |
| Methylophiopogonanone A (MO-A), a homoisoflavonoid extracted from Ophiopogon japonicus, has been shown to attenuate myocardial apoptosis and improve cerebral ischemia/reperfusion injury. However, the hypolipidemic effects remain unknown. This study was performed to investigate a potential hypolipidemic effect of MO-A in hyperlipidemia rats, as well as its underlying mechanism of action. A rat model of hyperlipidemia was induced by a high-fat diet (HFD). Animals were randomly divided into three groups (n=8/group): normal control group (NC), HFD group, and HFD+MO-A (10 mg·kg-1·d-1) treatment group. The effects of MO-A on serum lipids, body weight, activity of lipoprotein metabolism enzyme, and gene expression of lipid metabolism were evaluated in HFD-induced... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ophiopogon japonicus; PPARα; High-fat diet; Lipid lowering; Dyslipidemia. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2020000300609 |
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| Ceccato,M.G.B.; Bonolo,P.F.; Souza Neto,A.I.; Araújo,F.S.; Freitas,M.I.F.. |
| The aim of this study was to determine the impact of antiretroviral therapy on the lipid profile of human immunodeficiency virus (HIV) patients before and after the initiation of highly active antiretroviral therapy (HAART). This was a cross-sectional analysis of patients receiving HAART at a reference center in Belo Horizonte, Brazil, on the basis of medical records from 2002 to 2006. Patients were included if they had at least one lipid test or a clinical or laboratory diagnosis of dyslipidemia/lipodystrophy. Among the 692 patients, 620 met the eligibility criteria. The majority were males (66.5%), middle age (average 39 years), had a low educational level (60.4%), and low income (51.0%). HAART duration ranged from 11 days to 4.6 years, with a mean of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antiretroviral therapy; Dyslipidemia; Lipodystrophy; Management. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011001100015 |
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| Mendes-Lana,A.; Pena,G.G.; Freitas,S.N.; Lima,A.A.; Nicolato,R.L.C.; Nascimento-Neto,R.M.; Machado-Coelho,G.L.L.; Freitas,R.N.. |
| The influence of apolipoprotein E alleles and genotypes on plasma lipid levels was determined in 185 individuals of mixed ethnicity living in Ouro Preto, Brazil. DNA was obtained from blood samples and the genotypes were determined by an RFLP-PCR procedure. The *3 allele was the most frequent (72%), followed by *4 (20%) and *2 (8%); *4 frequency was higher and *2 frequency was lower in the dyslipidemic group than in the normal control group. The *2 carriers presented lower LDL and total cholesterol levels compared to the *3 and *4 carriers. All six expected genotypes were observed in the individuals genotyped: E2/2 (2.1%), E4/4 (2.7%), E2/4 (3.7%), E2/3 (8.0%), E3/3 (53.3%), E3/4 (29.9%); no difference in genotype frequencies was found between the normal... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Apolipoprotein E polymorphism; Lipids; Dyslipidemia; Brazilian population; Atherosclerosis. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000100007 |
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| Barcelos,A.L.V.; Chies,R.; Almeida,S.E.M.; Fiegenbaum,M.; Schweigert,I.D.; Chula,F.G.L.; Rossetti,M.L.; Silva,C.M.D.. |
| We investigated the effect of the -278A>C polymorphism in the CYP7A1 gene on the response of plasma lipids to a reduced-fat diet for 6 to 8 weeks in a group of 82 dyslipidemic males with a mean age of 46.0 ± 11.7 years. Individuals who presented at least one high alteration in total cholesterol, low-density lipoprotein cholesterol or triglyceride values were considered to be dyslipidemic. Exclusion criteria were secondary dyslipidemia due to diabetes mellitus, renal, liver, or thyroid disease. None of the subjects were using lipid-lowering medication. Baseline and follow-up lipid concentrations were measured. The genotypes were determined by the digestion of PCR products with the BsaI restriction endonuclease. There were statistically significant... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dyslipidemia; Polymorphisms; Diet; CYP7A1; Southern Brazil. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000600003 |
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| Registros recuperados: 22 | |
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