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THE USE OF SEROTHERAPHY TO REVERSE ECG and CARDIAC ENZYME CHANGES CAUSED BY SCORPION Mesobuthus tamulus concanesis, Pocock ENVENOMING J. Venom. Anim. Toxins
MURTHY,K. RADHA KRISHNA; ZARE,M. ABBAS; HAGHNAZARI,L..
Acute myocardiopathy in experimental dogs and rabbits was induced by subcutaneous (SQ) injection of 3.5 mg/kg of scorpion venom from Mesobuthus tamulus concanesis, Pocock. An increase in circulating lactic dehydrogenase (LDH), serum glutamic oxalacetic transaminase (SGOT), creatine kinase-MB isoenzyme (CK-MB), serum glutamine pyrovate transaminase (SGPT) and alpha hydroxy butyrate dehydrogenase (HBDH) enzyme levels was observed in dogs 60 min after venom injection, and a further rise was observed 120 min after venom injection. The administration of the species-specific scorpion antivenom (SAV) at different time intervals after venom injection resulted in reversal of electrocardiographic changes and a reduction in cardiac enzyme levels. The administration...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mesobuthus tamulus concanesis; Electrocardiography; Glutamicoxalacetate transaminase; Glutamine pyruvate transaminase; Lactate dehydrogenase; Creatine kinase/MB; Alpha hydroxy butyrate dehydrogenase.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301999000200004
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Cardiorespiratory evaluation of juvenile rats experimentally envenomed with Tityus serrulatus venom J. Venom. Anim. Toxins incl. Trop. Dis.
Pinto,MCL; Melo,MB; Cruz,ML; Verçosa Junior,D; Melo,MM.
Accidental envenomation caused by Tityus serrulatus scorpions is very common in Brazil and may result in serious cardiorespiratory alterations that are frequently fatal to children. In the present study, the effects of T. serrulatus venom on the cardiorespiratory system of recently weaned male Wistar rats were evaluated. Fifteen animals were distributed into three groups (n = 5). The control group A received 400 μL ultrapure water by subcutaneous injection, while the experimental groups B and C were injected with scorpion venom (100 and 450 μg, respectively, in 400 μL water). Electrocardiogram (ECG) traces were obtained prior to the experiment, at five-minute intervals up to 30 minutes after treatment. At 40 minutes after envenomation, the animals had...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Tityus serrulatus; Rats; Electrocardiography; CK; CK-MB; Troponin; Pulmonary hemorrhages.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000200008
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Cardiac evaluation after experimental intoxication by Amorimia rigida (Malpighiaceae) extracts in rabbits J. Venom. Anim. Toxins incl. Trop. Dis.
Borboleta,LR; Silva,EF; Oliveira,MS; Michel,AFRM; Ferraz,VP; Leite,RC; Melo,MM.
Clinical and laboratory changes were evaluated in rabbits after intoxication by Amorimia rigida, a plant that causes sudden death. Nine New Zealand male rabbits, averaging 3.54 kg, were categorized into three groups (n = 3) and received, for eight consecutive days, the equivalent of 30 g/kg dry matter of A. rigida water-soluble (SG) and water-insoluble (IG) extracts via nasoesophageal route. The control group received water. There were no alterations in creatine kinase enzyme (CK), CK myocardial fraction (CKMB) or troponine I (cTnI). None of the animals had clinical or electrocardiographic (conventional and Holter) alterations. There were progressive decreases in the left ventricular ejection fraction and systolic fractional shortening. Doppler...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Toxic plant; Amorimia rigida; Cardiac muscle profile; Electrocardiography; Echocardiography; Rabbit.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992012000300007
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Cardiorespiratory alterations in rodents experimentally envenomed with Hadruroides lunatus scorpion venom J. Venom. Anim. Toxins incl. Trop. Dis.
Costal-Oliveira,Fernanda; Guerra-Duarte,Clara; Oliveira,Maira Souza; Castro,Karen Larissa Pereira de; Lopes-de-Sousa,Leticia; Lara,Aline; Gomes,Enéas Ricardo de Morais; Bonilla,Cesar; Guatimosim,Sílvia; Melo,Marília Martins; Chávez-Olórtegui,Carlos.
Abstract Background Hadruroides lunatus is the most abundant scorpion species in the Peruvian central coast, where most of the accidents involving humans are registered. In spite of its prevalence, there are only very few studies on H. lunatus envenomation. The aim of the present study was to analyze the cardiorespiratory alterations caused by H. lunatus envenomation in rodents. Methods Wistar rats injected with H. lunatus scorpion venom were submitted to electrocardiography. After euthanasia, rat lungs were collected and histopathologically analyzed. Mouse cardiomyocytes were used to perform immunofluorescence and calcium transient assays. Data were analyzed by ANOVA or Student’s t-test. The significance level was set at p< 0.05. Results It was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hadruroides lunatus venom; Cardiorespiratory alterations; Electrocardiography; Immunofluorescence; Calcium transient.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992017000100301
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The electrocardiography on the veterinary medicine MV&Z
Ferreira, Wagner Luis; Souza, Rute Chamié Alves de; Camacho, Aparecido Antonio.
The objective of this article is to highlight the importance of the electrocardiography in veterinary medicine, revising the basic notions of the technique and its practical application for students and practitioners.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Electrocardiography; Veterinary medicine; Cardiology eletrocardiografia; Medicina veterinária; Cardiologia.
Ano: 1998 URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/3396
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Noninvasive method for electrocardiogram recording in conscious rats: feasibility for heart rate variability analysis Anais da ABC (AABC)
Pereira-Junior,Pedro P.; Marocolo,Moacir; Rodrigues,Fabricio P.; Medei,Emiliano; Nascimento,José H.M..
Heart rate variability (HRV) analysis consists in a well-established tool for the assessment of cardiac autonomic control, both in humans and in animal models. Conventional methods for HRV analysis in rats rely on conscious state electrocardiogram (ECG) recording based on prior invasive surgical procedures for electrodes/transmitters implants. The aim of the present study was to test a noninvasive and inexpensive method for ECG recording in conscious rats, assessing its feasibility for HRV analysis. A custom-made elastic cotton jacket was developed to fit the rat's mean thoracic circumference, with two pieces of platinum electrodes attached on its inner surface, allowing ECG to be recorded noninvasively in conscious, restrained rats (n=6). Time- and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Electrocardiography; Heart rate variability; Methodology; Noninvasive; Rat.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652010000200019
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Heart rate variability and arrhythmias evaluated with Holter in dogs with degenerative mitral valve disease Arq. Bras. Med. Vet. Zootec.
Oliveira,M.S.; Muzzi,R.A.L.; Araújo,R.B.; Muzzi,L.A.L.; Ferreira,D.F.; Silva,E.F..
Cardiac diseases promote alterations in the autonomic control of the heart, leading to an increase in heart rate and, as a result, a decrease in heart rate variability (HRV).The aim of this study was to evaluate if the development of heart failure secondary to degenerative mitral valve disease (DMVD) concurs with changes in autonomic modulation of heart rhythm which are assessed by long electrocardiography examination (Holter). Dogs were evaluated by clinical examination and echocardiography in order to be categorized into the following groups: Control (healthy; n=6), DMVD (disease without heart failure; n=8), and DMVD heart failure (disease with heart failure; n=13). Arrhythmias and frequency domain HRV were determined by Holter. Diseased animals, when...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Electrocardiography; Heart failure; Frequency-domain; Cardiology.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352014000200015
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Effect of exercise on cardiovascular parameters in search and rescue-trained dogs Arq. Bras. Med. Vet. Zootec.
Santos,P.O.P.R.; Santos,E.A.; Reis,A.C.; Santos,A.M.M.R.; Kuster,M.C.C.; Trivilin,L.O.; Aptekmann,K.P..
ABSTRACT Physical activity alters the cardiovascular system of dogs, depending on the exercise characteristics and the animal’s physical conditioning. Little is known about the cardiovascular changes in rescue-trained dogs. This study evaluated the cardiovascular responses to a search and rescue exercise session to differentiate these alterations from cases of exhaustion or some possible pathology. Nine healthy rescue-trained dogs that trained for at least one year were used. Seven German Shepherds and two Belgian Shepherd Malinois were evaluated twice, immediately before exercise (M0) and immediately after a 20-minute training (M1). Electrocardiographic, echocardiographic, and systemic blood pressure (SBP) measurements were performed at each evaluation....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Working dog; Blood pressure; Echocardiography; Electrocardiography; Exercise physiology.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352018000401036
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Clinical and histopathological features of myocarditis in dogs with visceral leishmaniasis Arq. Bras. Med. Vet. Zootec.
Santos,F.P. dos; Pascon,J.P.E.; Pereira,D.T.P.; Anjos,B.L.; Mistieri,M.L.A.; Silveira,I.D.; Porciuncula,M.L..
Visceral leishmaniasis (VL) is a cosmopolitan parasitic zoonosis that can promote myocarditis and heart rate changes in canine and human hosts. Thus, histopathological aspects of the myocardium and clinical, hematological, biochemical, radiological and electrocardiographic data were evaluated in a group of 36 dogs naturally infected with VL (VLG) and compared to data from 15 non-infected dogs (CG=Control Group). A prevalence of asymptomatic dogs was present in the CG (100%) and polysymptomatic dogs in the VLG (66%). In addition, two dogs in the VLG demonstrated systolic murmurs in the mitral valve region: one with a II/VI intensity and the other with a III/VI intensity. The mean values of RBC, hemoglobin and hematocrit were lower in dogs in VLG and were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Electrocardiography; Leishmania sp.; Visceral leishmaniasis; Dogs.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352015000601519
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An analysis of the electrocardiogram QT interval BJMBR
Koehler,N.R.; Zouvi,J.P.; Acevedo,L.A.; Sukienik,B.J.; Rabin,M..
No reports testing the efficacy of the use of the QT/RR ratio <1/2 for detecting a normal QTc interval were found in the literature. The objective of the present study was to determine if a QT/RR ratio <=1/2 can be considered to be equal to the normal QTc and to compare the QT and QTc measured and calculated clinically and by a computerized electrocardiograph. Ratios (140 QT/RR) of 28 successive electrocardiograms obtained from 28 consecutive patients in a tertiary level teaching hospital were analyzed clinically by 5 independent observers and by a computerized electrocardiograph. The QT/RR ratio provided 56% sensitivity and 78% specificity, with an area under the receiver operator characteristic curve of 75.8% (95%CI: 0.68 to 0.84). The divergence...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Electrocardiography; Long QT syndrome; Arrhythmia; QT interval.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000100004
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Electrocardiographic changes during low-dose, short-term therapy of cutaneous leishmaniasis with the pentavalent antimonial meglumine BJMBR
Ribeiro,A.L.P.; Drummond,J.B.; Volpini,A.C.; Andrade,A.C.; Passos,V.M.A..
The pentavalent antimonial (Sb5+) meglumine is the drug of choice for the treatment of cutaneous leishmaniasis (CL) in Brazil. Although the cardiotoxicity of high-dose, long-term Sb5+ therapy is well known, the use of low-dose, short-term meglumine has been considered to be safe and relatively free from significant cardiac effects. In order to investigate the cardiotoxicity of low-dose, short-term therapy with meglumine in cutaneous leishmaniasis, 62 CL patients treated with meglumine were studied. A standard ECG was obtained before and immediately after the first cycle of treatment (15 mg Sb5+ kg-1 day-1). The electrocardiographic interpretation was carried out blindly by two investigators using the Minnesota Code. There were no significant differences in...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Cutaneous leishmaniasis; Electrocardiography; QT interval.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000300008
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Noninvasive prognostic markers for cardiac death and ventricular arrhythmia in long-term follow-up of subjects with chronic Chagas' disease BJMBR
Benchimol-Barbosa,P.R..
The objective of the present study was to investigate clinical, echocardiographic and electrocardiographic (12-lead resting ECG, 24-h ambulatory ECG monitoring and signal-averaged ECG (SAECG)) parameters in subjects with chronic Chagas' disease in a long-term follow-up as prognostic markers for adverse outcomes. Fifty adult outpatients (34 to 74 years old, 31 females) staged according to Los Andes class I, II or III and complaining of palpitation were enrolled in a longitudinal study. SAECG was analyzed in time and frequency domains and the endpoint was a composite of cardiac death and ventricular tachycardia. During a follow-up of 84.2 ± 39.0 months, 34.0% of the patients developed adverse outcomes (9 cardiac deaths and 11 episodes of ventricular...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chagas' disease; Cardiomyopathy; Noninvasive prognostic assessment; Long-term follow-up study; Echocardiography; Electrocardiography.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000200003
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Dogs poisoned with Nerium oleander fresh leaves: clinical and electrocardiographic findings Ciência Rural
Camplesi,Annelise Carla; Bellodi,Carolina; Socha,José Javier Mesa; Hatayde,Mário Roberto; Sobreira,Márcia Ferreira da Rosa; Araujo,Gustavo Henrique Marques; Araujo,Carla Fredrichsen Moya.
ABSTRACT: Nerium oleander is distributed worldwide, mainly in tropical and subtropical regions. These shrubs are frequently used as ornamental plants. However, they contain more than 30 cardiac glycosides that can cause serious toxic effects in dogs. The objective of this study was to report the clinical and electrocardiographic alterations in dogs experimentally poisoned with N. oleander. Ten adult, healthy, mixed-breed dogs weighing 10-25kg and aged 3-6 years were selected for the study. We orally administered 0.25g kg-1 of fresh ground leaves of N. oleander to the dogs. No dog died after the ingestion, but all exhibited signs of poisoning such as vomiting, sialorrhea, nausea, apathy, conjunctiva congestion, dehydration, abdominal pain, tremors,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Blood pressure; Arrhythmia; Electrocardiography; Cardiac glycosides; Canine.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000600553
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Electrocardiographic study on geriatric dogs undergoing general anesthesia with isoflurane Ciência Rural
Conti-Patara,Andreza; Fantoni,Denise Tabacchi; Cortopassi,Silvia Renata Gaido.
The purpose of this study was to clarify the degree of influence of anesthetic agents commonly used during anesthesia on the heart conduction systems of geriatric dogs, with or without the presence of electrocardiographic changes in the pre-anesthetic electrocardiogram and also to determine the possible causes of ST-segment and T-wave changes during anesthesia, by monitoring ventilation and oxygenation. 36 geriatric dogs were evaluated. In addition to electrocardiographic evaluation, the pre-anesthetic study included serum levels of urea, creatinine, total protein, albumin and electrolytes. The pre-anesthetic medication consisted of acepromazine (0.05mg kg-1) in association with meperidine (3.0mg kg-1) by IM injection. Anesthesia was induced with propofol...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Anesthesia; Dog; Electrocardiography; Geriatrics.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782009000200021
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