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Is the emergence of fungal resistance to medical triazoles related to their use in the agroecosystems? A mini review 58
Ribas e Ribas,Aícha Daniela; Spolti,Pierri; Del Ponte,Emerson Medeiros; Donato,Katarzyna Zawada; Schrekker,Henri; Fuentefria,Alexandre Meneghello.
Abstract Triazole fungicides are used broadly for the control of infectious diseases of both humans and plants. The surge in resistance to triazoles among pathogenic populations is an emergent issue both in agriculture and medicine. The non-rational use of fungicides with site-specific modes of action, such as the triazoles, may increase the risk of antifungal resistance development. In the medical field, the surge of resistant fungal isolates has been related to the intensive and recurrent therapeutic use of a limited number of triazoles for the treatment and prophylaxis of many mycoses. Similarities in the mode of action of triazole fungicides used in these two fields may lead to cross-resistance, thus expanding the spectrum of resistance to multiple...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cross-resistance; Emerging fungal pathogens; Fungicide sensitivity; Agriculture; Medicine.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000400793
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