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Voluntary wheel running: patterns and physiological effects in mice BJMBR
Manzanares,G.; Brito-da-Silva,G.; Gandra,P.G..
Exercise can prevent and improve the pathophysiology of diseases and promote healthy aging. Thus, understanding the mechanisms that regulate the beneficial effects of exercise may lead to the development of new strategies to enhance quality of life and to counteract chronic diseases. Voluntary wheel running is an interesting model to study the effects of exercise in mice. Compared to forced treadmill exercise, voluntary wheel running presents several advantages such as: 1) running pattern is similar to natural running behavior of mice; 2) it is performed under non-stressed conditions, according to the rhythmicity of the animal; 3) it does not require direct interference from the researcher, and can be easily applied in long-term studies. Mice run...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Voluntary wheel running; Mouse; Exercise; Skeletal muscle; Endurance adaptation.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000100301
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