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| Leesombun, Arpron; Boonmasawai, Sookruetai; Nishikawa, Yoshifumi. |
| Neosporosis has a worldwide distribution and causes economic losses in farming, particularly by increasing the risk of abortion in cattle. This study investigated the effects of Thai piperaceae (Piper betle, P. nigrum, and P. sarmentosum) extracts on Neospora caninum infections in vitro and in vivo. In an in vitro parasite growth assay based on the green fluorescent protein (GFP) signal, P. betle was the most effective extract at inhibiting parasite growth in human foreskin fibroblast cells (IC50 of GFP-expressing N. caninum parasites, 22.1 mu g/ml). The P. betle extract, at 25 mu g per ml, inhibited parasite invasion into host cells. Furthermore, in two independent experiments, treating N. caninum-infected mice with the P. betle extract for 7 days... |
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Palavras-chave: Neospora caninum; Neosporosis; Piper betle; Piper nigrum; Piper sarmentosum; Ethanol extract. |
| Ano: 2017 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4578 |
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| Rennó,Magdalena N.; Barbosa,Gleyce M.; Zancan,Patricia; Veiga,Venicio F.; Alviano,Celuta S.; Sola-Penna,Mauro; Menezes,Fábio S.; Holandino,Carla. |
| Plant-derived substances have been considered as important sources of drugs, including antineoplasic agents. Babassu mesocarp is popularly used in Brazil as a food additive, and in popular medicine against several conditions, such as inflammations, menstrual pains and leukaemia. From babassu Orbignya speciosa (Mart.) Barb. Rodr. [Arecaceae (Palmae)] epicarp/mesocarp, an ethanol extract was prepared and named OSEME, which was tested on the viability,morphology and metabolism of several cell lines, such as the leukaemic cell lines, HL-60, K562 and the latter multidrug resistant counterpart K562-Lucena 1, the human breast cancer cell line MCF-7, the mouse fibroblast cell line 3T3-L1 and fresh human lymphocytes. OSEME promoted a dose-dependent decrease on the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antitumoral agents; Ethanol extract; Orbignya speciosa. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652008000300008 |
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| Lou,Zhaohuan; Wang,Junwei; Chen,Yingjun; Xu,Chandi; Chen,Xinyi; Shao,Tiejuan; Zhang,Kena; Pan,Hongying. |
| This study aimed to explore the influence of gut microbiota alterations induced by Linderae radix ethanol extract (LREE) on alcoholic liver disease (ALD) in rats and to study the anti-inflammatory effect of LREE on ALD through the lipopolysaccharide (LPS) toll-like receptor 4 (TLR4)-nuclear factor kappa B (NF-κB) pathway. ALD rat models were established by intragastric liquor [50% (v/v) ethanol] administration at 10 mL/kg body weight for 20 days. Rats were divided into six groups: normal group (no treatment), model group (ALD rats), Essentiale group (ALD rats fed with Essentiale, 137 mg/kg), and LREE high/moderate/low dose groups (ALD rats fed with 4, 2, or 1 g LREE/kg). NF-κB and LPS levels were evaluated. Liver pathological changes and intestinal... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Lindera aggregata (Sims) Kosterm; Ethanol extract; Alcoholic liver disease; Intestinal endotoxemia; 16S ribosomal RNA gene sequencing; Tight junction protein. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000600601 |
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| Chiffelle,Italo; Huerta,Amanda; Azúa,Fernando; Puga,Karla; Araya,Jaime E. |
| Xanthogaleruca luteola Müller (Coleoptera: Chrysomelidae), a defoliator of Ulmus species currently present in several regions of central Chile, causes severe damage to trees, mainly in park areas, street tree-lines and gardens. The antifeeding and insecticidal activities of extracts from immature fruit of Melia azedarach L. (Meliaceae) were determined on adults of X. luteola in laboratory bioassays. Several concentrations of the extracts obtained with water and ethanol were used and their effectiveness and LC50 were determined. The antifeeding action of the water extracts caused 100% deterrence over concentrations of 3.6% w/v. Both extracts were effective insecticides against adults, causing 86% mortality (2.4% w/v), with a better performance of the... |
| Tipo: Journal article |
Palavras-chave: Botanical insecticides; Ethanol extract; Water extract. |
| Ano: 2011 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-58392011000200006 |
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