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| Martins,Alex Tadeu; Santos,Fabiano de Sant´Ana dos; Scannavino,Fábio Luiz Ferreira; Pires,Juliana Rico; Zuza,Elizângela Partata; Junior,João Armando Padovani; Azoubel,Reinaldo; Di Mateo,Miguel Angel Sala; Lopes,Ruberval Armando. |
| The cyclamate, a sweetner substance derived from N-cyclo-hexyl-sulfamic acid, is largely utilized as a non-caloric artificial edulcorant in foods and beverages as well as in the pharmaceutical industry. The objective of this study was to evaluate karyometric and stereological alterations in the rat fetal pancreas resulting from the intraperitoneal administration of sodium cyclamate. The exocrine pancreas of ten fetuses of rats were evaluated, five treated and five controls chosen at random, in which five rats that received from the 10th to 14th days of pregnancy an intraperitoneal daily injection of sodium cyclamate at 60 mg/Kg of body weight during 5 days. At the 20th day of gestation, the animals were removed and weighed, as were their placentas; the... |
| Tipo: Journal article |
Palavras-chave: Sodium cyclamate; Exocrine pancreas; Karyometry; Stereology. |
| Ano: 2010 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000300038 |
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