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| Ding,Fang; Yuan,Xin; Li,Qingqing; Sun,Wenqiang; Gan,Chao; He,Hua; Song,Chenling; Wang,Jiwen. |
| Background Fatty acid synthase (FAS) is a key enzyme of de novo lipogenesis (DNL), which has been cloned from several species: Gallus gallus, Mus musculus, Homo sapiens, but not from Anas platyrhynchos. The current study was conducted to obtain the full-length coding sequence of Peking duck FAS and investigate its expression during adipocyte differentiation. Results We have isolated a 7654 bp fragment from Peking duck adipocytes that corresponds to the FAS gene. The cloned fragment contains an open reading frame of 7545 bp, encodes a 2515 amino acid protein, and displays high nucleotide and amino acid homology to avian FAS orthologs. Twelve hour treatment of oleic acid significantly up-regulated the expression of FAS in duck preadipocytes (P < 0.05).... |
| Tipo: Journal article |
Palavras-chave: Expression pattern; FAS; Oleic acid; Peking duck. |
| Ano: 2014 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582014000600001 |
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| Momino,Wakana; Félix,Têmis Maria; Abeche,Alberto Mantovani; Zandoná,Denise Isabel; Scheibler,Gabriela Gayer; Chambers,Christina; Jones,Kenneth Lyons; Flores,Renato Zamora; Schüler-Faccini,Lavínia. |
| Prenatal alcohol exposure can have serious and permanent adverse effects. The developing brain is the most vulnerable organ to the insults of prenatal alcohol exposure. A behavioral phenotype of prenatal alcohol exposure including conduct disorders is also described. This study on a sample of Brazilian adolescents convicted for criminal behavior aimed to evaluate possible clinical features of Fetal Alcohol Syndrome (FAS). These were compared to a control group of school adolescents, as well as tested for other environmental risk factors for antisocial behavior. A sample of 262 institutionalized male adolescents due to criminal behavior and 154 male students aged between 13 and 21 years comprised the study population. Maternal use of alcohol was admitted by... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Prenatal alcohol exposure; Fetal alcohol spectrum disorder; Criminal behavior; Conduct disorder; FAS; FASD. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000600011 |
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