This work aimed at evaluating the characteristics of thirty nine insecticides on tissue distribution and accumulation, using their physico-chemical characteristics and the tissues lipid contents to calculate the compounds distribution among the tissues. The insecticides evaluated were selected among those registered in Brazil for agriculture use. The level I fugacity model was used for the calculations of insecticide distribution among the tissues of muscles, viscera, skin, fat, blood, liver, kidneys and gut. The octanol-water partition coefficient, water solubility and tissue lipid contents showed an insecticide distribution in human tissues. Cluster analysis was performed aiming the identification and separation of insecticides groups based on their... |