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A snapshot of cancer in Chile: analytical frameworks for developing a cancer policy Biol. Res.
la Jara,Jorge Jimenez de; Bastias,Gabriel; Ferreccio,Catterina; Moscoso,Cristian; Sagues,Sofia; Cid,Camilo; Bronstein,Eduardo; Herrera,Cristian; Nervi,Bruno; Corvalan,Alejandro; Velasquez,Ethel V; Gonzalez,Pamela; Castellon,Enrique; Bustamante,Eva; Oñate,Sergio; McNerney,Eileen; Sullivan,Richard; Owen,Gareth I.
INTRODUCTION: The South American country Chile now boasts a life expectancy of over 80 years. As a consequence, Chile now faces the increasing social and economic burden of cancer and must implement political policy to deliver equitable cancer care. Hindering the development of a national cancer policy is the lack of comprehensive analysis of cancer infrastructure and economic impact. OBJECTIVES: Evaluate existing cancer policy, the extent of national investigation and the socio-economic impact of cancer to deliver guidelines for the framing of an equitable national cancer policy. METHODS: Burden, research and care-policy systems were assessed by triangulating objective system metrics -epidemiological, economic, etc. - with political and policy analysis....
Tipo: Journal article Palavras-chave: Chile; Cancer policy; Investigation; Research and development; Statistics; Gallbladder cancer; Stomach cancer; Developing country.
Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100010
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Tea polyphenols induce S phase arrest and apoptosis in gallbladder cancer cells BJMBR
Wang,Jiaqi; Pan,Yixuan; Hu,Jiacheng; Ma,Qiang; Xu,Yi; Zhang,Yijian; Zhang,Fei; Liu,Yingbin.
Gallbladder cancer (GBC) is the most common malignancy in the biliary tract. Without effective treatment, its prognosis is notoriously poor. Tea polyphenols (TPs) have many pharmacological and health benefits, including antioxidant, anti-inflammatory, anti-tumor, anti-thrombotic, antibacterial, and vasodilatory properties. However, the anti-cancer effect of TPs in human gallbladder cancer has not yet been determined. Cell viability and colony formation assay were used to investigate the cell growth. Cell cycle and apoptosis were evaluated by flow cytometry analysis. Western blot assay was used to detect the expression of proteins related to cell cycle and apoptosis. Human tumor xenografts were used to examine the effect of TPs on gallbladder cancer cells...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Gallbladder cancer; Tea polyphenols; Apoptosis.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000400614
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