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Coping styles in European sea bass: The link between boldness, stress response and neurogenesis ArchiMer
Alfonso, Sebastien; Sadoul, Bastien; Gesto, Manuel; Joassard, Lucette; Chatain, Beatrice; Geffroy, Benjamin; Bégout, Marie-laure.
Coping styles consist of a coherent set of individual physiological and behavioral differences in stress responses that are consistent across time and context. Such consistent inter-individual differences in behavior have already been shown in European sea bass (Dicentrarchus labrax), but the associated mechanisms are still poorly understood. Here, we combine physiological measurements with individual behavioral responses in order to characterize coping styles in fish. Fish were tagged and placed in a tank for group risk-taking tests (GRT) at 8 months of age to evaluate boldness using the proxy latency of leaving a sheltered area towards an open area. A subsample of these fish were individually challenged 16 months later using an open field test (OFT), in...
Tipo: Text Palavras-chave: Personality; HPI axis; Gene transcription; Neurotransmitters.
Ano: 2019 URL: https://archimer.ifremer.fr/doc/00491/60282/63708.pdf
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NFAT regulates CSF-1 gene transcription triggered by L-selectin crosslinking Biocell
Chen,Cuixia; Cui,Lingling; Shang,Xin; Zeng,Xianlu.
L-selectin is a member of the selectin family that play an important role both in mediating the initial capture and subsequent rolling of leukocytes along the endothelial cells. Furthermore, L-selectin can function as a signal molecule. In our previous studies, we reported that L-selectin ligation could regulate CSF-1 (colony-stimulating factor-1) gene transcription, in which AP-1 acts as a crucial transcriptional factor. Here we investigated the function of the NFAT in the CSF-1 gene transcriptional events. We found that overexpression of WT NFAT induce CSF-1 gene transcription greatly in the activated Jurkat cells. Furthermore, we found that NFAT can be recruited to the nucleus after L-selectin ligation, and the nuclear NFAT interacts with the CSF-1...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Signal transduction; Gene transcription; Nuclear transcriptional factor.
Ano: 2010 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452010000200001
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