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	Provedor de dados BABT (1) Autor Toğar,Başak (1) Türkez,Hasan (1) Çelik,Kübra (1) Palavra-chave Antioxidant activity (1) Cytotoxicity (1) Genotoxicity (1) Guaiazulene (1) Oxidant status (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2015 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última In vitro cytotoxic, genotoxic and antioxidant/oxidant effects of guaiazulene on human lymphocytes BABT Toğar,Başak; Çelik,Kübra; Türkez,Hasan. The aim of this study was to evaluate for the cytotoxicity, genotoxicity and antioxidant/oxidant activity of GYZ on human peripheral blood lymphocytes (PBLs). Guaiazulene (GYZ) was added into culture tubes at various concentrations (0-400 µg/mL-1). Cytotoxicity against the human lymphocytes cultures was examined by lactate dehydrogenase (LDH) release assay. The proliferative response was estimated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay. Antioxidant/oxidant activity was evaluated by measuring the total oxidant status (TOS) and total antioxidant capacity (TAC) levels. Micronucleus (MN) and chromosomal aberration (CA) tests were used in genotoxicity studies. The results showed that GYZ caused cytotoxicity in the PBLs at... Tipo: Info:eu-repo/semantics/article Palavras-chave: Guaiazulene; Cytotoxicity; Genotoxicity; Antioxidant activity; Oxidant status. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000100061 Registros recuperados: 1 Primeira ... 1 ... Última

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