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	Provedor de dados Biol. Res. (1) Autor Cisternas,Javier (1) Flores,Sergio V (1) Valenzuela,Carlos Y (1) Palavra-chave Bose-Einstein distribution (1) Fxations (1) HIV-1 env gene (1) Neutral evolution (1) Pan-selective evolution (1) Tipo do documento Journal article (1) Ano 2010 (1) País Chile (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Fixations of the HIV-1 env gene refute neutralism: New evidence for pan-selective evolution Biol. Res. Valenzuela,Carlos Y; Flores,Sergio V; Cisternas,Javier. We examined 103 nucleotide sequences of the HIV-1 env gene, sampled from 35 countries and tested: I) the random (neutral) distribution of the number of nucleotide changes; II) the proportion of bases at molecular equilibrium; III) the neutral expected homogeneity of the distribution of new fxated bases; IV) the hypothesis of the neighbor infuence on the mutation rates in a site. The expected random number of fxations per site was estimated by Bose-Einstein statistics, and the expected frequencies of bases by matrices of mutation-fxation rates. The homogeneity of new fxations was analyzed using χ2 and trinomial tests for homogeneity. Fixations of the central base in trinucleotides were used to test the neighbor infuence on base substitutions.... Tipo: Journal article Palavras-chave: Bose-Einstein distribution; Fxations; HIV-1 env gene; Neutral evolution; Pan-selective evolution. Ano: 2010 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602010000200002 Registros recuperados: 1 Primeira ... 1 ... Última

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