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| Souza,P.C.; Ocarino,N.M.; Tavares,W.L.F.; Boeloni,J.N.; Cassali,G.D.; Serakides,R.. |
| Mitotic index, nuclear diameter, number of nucleolar organizing regions, and Ki-67 expression, in hair follicle tumors of 82 dogs were evaluated. Tissue specimens were used to prepare sections for histological staining for number of nucleolar organizing region and immunohistochemical staining for Ki-67. Tumors were classified as trichoblastoma (n=32), benign trichoepithelioma (n=30), pilomatricoma (n=7), malignant trichoepithelioma (n=6), infundibular keratinizing acanthoma (n=5), and tricholemmoma (n=2). Head, dorsum, and limbs were the most affected sites. Malignant trichoepithelioma presented significantly higher mitotic index, number of nucleolar organizing regions and Ki-67 expression. Regarding benign neoplasms, trichoblastoma presented significantly... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dog; Neoplasm; AgNOR; Hair follicle; Ki-67. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352008000500006 |
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| Forni,Maria F; Trombetta-Lima,Marina; Sogayar,Mari C. |
| The skin is a complex stratified organ which acts not only as a permeability barrier and defense against external agents, but also has essential thermoregulatory, sensory and metabolic functions. Due to its high versatility and activity, the skin undergoes continuous self-renewal to repair damaged tissue and replace old cells. Consequently, the skin is a reservoir for adult stem cells of different embryonic origins. Skin stem cell populations reside in the adult hair follicle, sebaceous gland, dermis and epidermis. However, the origin of most of the stem cell populations found in the adult epidermis is still unknown. Far more unknown is the embryonic origin of other stem cells that populate the other layers of this tissue. In this review we attempt to... |
| Tipo: Journal article |
Palavras-chave: Skin development; Embryonic skin; Epidermis; Dermis; Sebaceous Gland; Hair follicle. |
| Ano: 2012 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000300003 |
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| Watanabe, Ken-ichi; Chambers, James K.; Uchida, Kazuyuki; Nibe, Kazumi; Ushio, Nanako; Horiuchi, Noriyuki; Kobayashi, Yoshiyasu; Nakayama, Hiroyuki. |
| The atypical cutaneous tumor of a 9-year-old mixed breed female dog was examined. The tumor was well-demarcated and histologically composed of a trichoblastic area, tricholemmal area and apocrine glandular area. Neoplastic cells in trichoblastic area and tricholemmal area had PAS-positive granules in the cytoplasm and were positive for pan-cytokeratin, cytokeratin 5/6, 14 and 19 and p63. Neoplastic cells in trichoblastic area were also positive for cytokeratin 15 and CD34. Neoplastic cells in apocrine glandular area were positive for pan-cytokeratin and cytokeratin 7,18 and 19. Myoepithelial cell proliferation with osteocartilaginous metaplasia was observed in this area. Since neoplastic cells showed multiphenotypic differentiation for hair follicles and... |
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Palavras-chave: Cutaneous mixed tumor; Dog; Hair follicle; Multiphenotypic differentiation. |
| Ano: 2017 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4453 |
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