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	Provedor de dados AgEcon (1) Autor Amos, Christopher I. (1) Carroll, Raymond J. (1) Gutierrez, Roberto G. (1) Lin, Danyu Y. (1) Marchenko, Yulia V. (1) Palavra-chave Case–control data (1) Haplologit (1) Haplotype-based analysis (1) Haplotype–environment independence (1) Hardy–Weinberg equilibrium (1) Profile likelihood (1) Research Methods/ Statistical Methods (1) Retrospective study (1) Single nucleotide polymorphisms (SNPs) (1) Mais... Tipo do documento Article (1) Ano 2008 (1) País United States (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Semiparametric analysis of case–control genetic data in the presence of environmental factors AgEcon Marchenko, Yulia V.; Carroll, Raymond J.; Lin, Danyu Y.; Amos, Christopher I.; Gutierrez, Roberto G.. In the past decade, many statistical methods have been proposed for the analysis of case–control genetic data with an emphasis on haplotype-based disease association studies. Most of the methodology has concentrated on the estimation of genetic (haplotype) main effects. Most methods accounted for environmental and gene–environment interaction effects by using prospective-type analyses that may lead to biased estimates when used with case–control data. Several recent publications addressed the issue of retrospective sampling in the analysis of case–control genetic data in the presence of environmental factors by developing efficient semiparametric statistical methods. This article describes the new Stata command haplologit, which implements efficient... Tipo: Article Palavras-chave: Haplologit; Haplotype-based analysis; Haplotype–environment independence; Case–control data; Hardy–Weinberg equilibrium; Profile likelihood; Retrospective study; Single nucleotide polymorphisms (SNPs); Research Methods/ Statistical Methods. Ano: 2008 URL: http://purl.umn.edu/122596 Registros recuperados: 1 Primeira ... 1 ... Última

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