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| Registros recuperados: 21 | |
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| Jalali,A; Pipelzadeh,M H; Seyedian,R; Rahmani,A H; Omidian,N. |
| The available Razi Institute antivenom is still, empirically, used by intramuscular (IM) administration for the treatment of scorpion stings in humans by six medically dangerous species including Hemiscorpius lepturus (H. lepturus). The aim of this study was to assess the neutralizing ability and effectiveness of the antivenom in inhibiting hemoglobinuria, biochemical changes, increased microalbuminuria and urinary lactate dehydrogenase (LDH) following H. lepturus sting. Simultaneous intramuscular administration of 10 μL and 100 μL of antivenom, after 24 hours, had no significant preventive effect on the extent and degree of hemoglobinuria or proteinuria produced in venom-treated rats. After IM administration of antivenom, no significant changes in... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hemiscorpius lepturus; Scorpion; Venom; Hemolysis; Antivenom. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000200004 |
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| Troiano,J. C.; Gould,E. G.; Gould,I.. |
| A comparative study on the sensitivity of erythrocytes from different vertebrate species (avian, mammalian and reptilian) to the hemolytic action caused by cardiotoxin isolated from Naja naja atra venom was carried out. Cardiotoxin was able to induce direct hemolysis in washed erythrocytes from several animals, except for llama. The EC50 values from hemolysis of the most sensitive (cat) and the most resistant (snake) animal varied approximately tenfold. According to the cell behavior, it was possible to characterize four types of behavior: The first was observed in cat, horse and human cells; the second in rat, rabbit and dog erythrocytes; and the third only in llama erythrocytes, which were resistant to cardiotoxin concentrations up to 300 µg/ml. Finally,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hemolysis; Cobra; Venom; Erythrocytes; Animals. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000100004 |
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| García-Arredondo,Alejandro; Rojas-Molina,Alejandra; Ibarra-Alvarado,César; Lazcano-Pérez,Fernando; Arreguín-Espinosa,Roberto; Sánchez-Rodríguez,Judith. |
| Abstract Background: Scleractinian corals (stony corals) are the most abundant reef-forming cnidarians found in coral reefs throughout the world. Despite their abundance and ecological importance, information about the diversity of their toxins and their biological activities is very scarce. In this study, the chemical composition and the biological activities of the aqueous extracts of Pseudodiploria strigosa, Porites astreoides and Siderastrea siderea, three scleractinian corals from the Mexican Caribbean, have been assessed for the first time. Methods: Toxicity of the extracts was assessed in crickets; the presence of cytolysins was detected by the hemolysis assay; the vasoconstrictor activity was determined by the isolated rat aortic ring assay; the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Scleractinia; Pseudodiploria strigosa; Porites astreoides; Siderastrea siderea; Toxicity; Hemolysis; Vasoconstriction; Nociceptive response. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992016000100323 |
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| Wei,Shuangshuang; Chi,Tingting; Meng,Aiyun; Chen,Congwei; An,Tianchen; Wang,Manchuriga; Zhang,Yingxia. |
| Background The hemolytic activity of skin secretions obtained by stimulating the frog Kaloula pulchra hainana with diethyl ether was tested using human, cattle, rabbit, and chicken erythrocytes. The skin secretions had a significant concentration-dependent hemolytic effect on erythrocytes. The hemolytic activity of the skin secretions was studied in the presence of osmotic protectants (polyethylene glycols and carbohydrates), cations (Mg2+, Ca2+, Ba2+, Cu2+, and K+), or antioxidants (ascorbic acid, reduced glutathione, and cysteine). Results Depending on their molecular mass, osmotic protectants effectively inhibited hemolysis. The inhibition of skin hemolysis was observed after treatment with polyethylene glycols (1000, 3400, and 6000 Da). Among divalent... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Amphibian; Skin secretions; Hemolysis; Pore-forming. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992013000100306 |
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| Hernández-Matehuala,Rosalina; Rojas-Molina,Alejandra; Vuelvas-Solórzano,Alma Angelica; Garcia-Arredondo,Alejandro; Ibarra Alvarado,Cesar; Olguín-López,Norma; Aguilar,Manuel. |
| AbstractBackground Millepora alcicornis is a branching hydrocoral common throughout the Caribbean Sea. Like other members of this genus, this species is capable of inducing skin eruptions and blisters with severe pain after contact. In the present study, we investigated the toxicity of theM. alcicornis aqueous extract on several animal models. Considering that some cnidarian hemolysins have been associated to local tissue damage, since they also induce lysis of other cell types, we also made a partial characterization of the hemolytic activity of M. alcicornis aqueous extract. This information is important for understanding the defense mechanisms of the “fire corals”.Methods The effects of pH, temperature, and some divalent cations on the hemolytic... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Fire coral; Millepora alcicornis; Hemolysis; Systemic toxicity; Electronic microscopy. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992015000100342 |
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| Moura,Raniere M.; Melo,Arthur A.; Carneiro,Rômulo F.; Rodrigues,Cícera R.f.; Delatorre,Plínio; Nascimento,Kyria S.; Saker-Sampaio,Silvana; Nagano,Celso S.; Cavada,Benildo S.; Sampaio,Alexandre H.. |
| Twenty species of marine invertebrates from the Brazilian coast were screened for hemagglutinating/hemolytic activity. In at least twelve tested species, hemagglutinating activity was different for different blood types, suggesting the presence of lectins. Extracts from four species showed hemolytic activity. Two new lectins were purified from the marine sponge Cliona varians (CvL-2) and sea cucumber Holothuria grisea (HGL). CvL-2 was able to agglutinate rabbit erythrocytes and was inhibited by galactosides. The hemagglutinating activity was optimal in pH neutral and temperatures below 70 °C. CvL-2 is a trimeric protein with subunits of 175 kDa. On the other hand, HGL showed both hemagglutinating and hemolytic activity in human and rabbit erythrocytes, but... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Purification; Hemolysis; Cytotoxicity; Galactose. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000200973 |
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| BIANCHINI,MATHEUS C.; GALVÃO,DENNYURA O.; TAMBORENA,TATIANA; ALVES,CLAUDIA O.; PUNTEL,ROBSON L.. |
| ABSTRACT Mentha pulegium (Lamiaceae) tea has been used as a traditional medicine; however, the modulatory effect of M. pulegium extracts on damage to human erythrocytes associated to t-butyl hydroperoxide (t-BHP) exposure remains to be investigated. Accordingly, we perform this study in order to test the hypothesis that aqueous and ethanolic extracts of M. pulegium could modulate the hemolysis associated to t-BHP exposure, non-protein thiol (NPSH) oxidation and lipid peroxidation (measured as thiobarbituric acid reactive substances - TBARS) in human erythrocytes. Samples were co-incubated with t-BHP (4 mmol/L) and/or aqueous or ethanolic extracts (10-1000 mg/mL) during 120 min to further analysis. We found that both extracts, when associated to t-BHP,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Mentha pulegium; Lamiaceae; Hemolysis; Lipid peroxidation; NPSH oxidation; Erythrocytes.. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000602901 |
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| Lopes,E.S.; Cardoso,W.M.; Nishi,D.M.; Horn,R.V.; Albuquerque,Á.H.; Lima,S.V.G.; Beleza,A.J.F.; Gaio,F.C.; Carmo,C.C.; Pascoal Filho,M.N.; Teixeira,R.S.C.. |
| ABSTRACT This study aimed to identify serogroups of Escherichia coli important for human health in isolates from psittacine of illegal wildlife trade in Ceará State. In addition, hemolysis and production of Extended Spectrum Beta-Lactamases (ESBL) was assessed in the isolates. A total of 78 E. coli strains isolated from different Psittaciformes species from a wildlife rehabilitation center in Fortaleza, Brazil. The isolates used in this study were previously identified and stored. Serogroup identification was performed using polyvalent sera for EPEC (O55, O111, O119, O114, O125, O86, O126, O127, O128), EIEC (O136, O124) and EHEC (O157). ESBL detection was performed with double disk synergy method. For hemolysis detection, isolates were inoculated in blood... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Escherichia coli; Serogroups; ESBL; Hemolysis. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352018000300823 |
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| Saruc,M.; Yuceyar,H.; Turkel,N.; Ozutemiz,O.; Tuzcuoglu,I.; Yuce,G.; Huseyinov,A.. |
| The literature indicates that acute pancreatitis is a complication of massive hemolysis with a prevalence of about 20%. We describe an experimental model of hemolysis-induced acute pancreatitis. Hemolytic anemia was induced in rats by a single ip injection of 60 mg/kg of 20 mg/ml acetylphenylhydrazine (APH) in 20% (v/v) ethanol on the first experimental day (day 0). One hundred and fifty Wistar albino rats weighing 180-200 g were divided into three groups of 50 animals each: groups 1, 2 and 3 were injected ip with APH, 20% ethanol, and physiological saline, respectively. Ten rats from each group were sacrificed on study days 1, 2, 3, 4 and 5. Serum amylase, lipase levels and pancreatic tissue tumor necrosis factor-alpha (TNF-alpha) and platelet-activating... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hemolysis; Pancreatitis model; Experimental pancreatitis; Etiology; Pathology. |
| Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000700008 |
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| Bizani,Delmar; Brandelli,Adriano. |
| The presence of Aeromonas spp. in food has been demonstrated. They are often introduced from water, which is the natural habitat of many species and is thought to be the main source of contamination. The occurrence of Aeromonas spp. was investigated in 70 water samples of a bovine abattoir. Aeromonas spp. were present in 21.4% of water samples. A. hydrophila was isolated from 11.4% of supplying water samples and from 25.7% of the water drained from carcasses, whereas A. sobria was sole isolated from 5.7% of supplying water samples. Although greater number of positive samples were from water drained from carcasses, only A. hydrophila isolates were present. This suggests that the supplying water is the source of contamination. The antibiotic susceptibility... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Aeromonas; Antibiotic activity; Aquatic environment; Hemolysis; Water. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822001000400016 |
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| Gatto,Larissa Junqueira; Fabri,Natasha Tiemi; Souza,Angela Maria de; Fonseca,Natasha Stopinski Triaquim da; Furusho,Alethéia dos Santos; Miguel,Obdulio Gomes; Dias,Josiane de Fatima Gaspari; Zanin,Sandra Maria Warumby; Miguel,Marilis Dallarmi. |
| Myrcia hatschbachii D. Legrand (Myrtaceae) is a native and endemic species from Brazil. This study investigated the essential oil composition, phytotoxic potential, in vitro toxicity, antioxidant properties and antibacterial activity of species. Chromatographic analysis of essential oil identified trans-calamanene, (E)-caryophyllene and spathulenol as major components. Antioxidant capacity was determined by the DPPH• scavenging method and phosphomolybdenum complex formation assay. Antibacterial activity was evaluated using the Minimal Inhibitory Concentration test, demonstrating that the essential oil was active toward Enterococcus faecalis and Staphylococcus aureus. Phytotoxic activity of essential oil was analyzed by testing interference on germination... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Essential oil; Phytotoxic; Antioxidant; Antibacterial; Hemolysis; Artemia salina. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100560 |
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| Registros recuperados: 21 | |
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