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	Provedor de dados J. Venom. Anim. Toxins incl. Trop. Dis. (3) BABT (1) BJMBR (1) J. Venom. Anim. Toxins (1) Autor Anjolette,Fernando A. P. (1) Arantes,Eliane C. (1) Avila-Soria,G. (1) Azzolini,Ana Elisa C. S (1) Bon,C (1) Bordon,Karla C. F. (1) Burnett,J. W. (1) Cerveñansky,C. (1) Channe Gowda,D. (1) Duran,R. (1) Freitas,J.C. (1) Hyslop,S (1) Lagos,P. (1) Leite,Flávia P. (1) Martins,LJ (1) Murari,S. K. (1) Pereira,Juliana C. (1) Pereira-Crott,Luciana S. (1) Pujatti,Priscilla Brunelli (1) Ramos-Aguilar,M. E. (1) Mais... Palavra-chave Hemolytic activity (6) Aurelia aurita (1) Bothrops lanceolatus (1) Bunodosoma cangicum (1) Complement system (1) Crab nerve (1) Crustacean lethality (1) Indian cobra (1) Labeling (1) Naja naja (1) Neurotoxins (1) Neutrophil chemotaxis (1) Phospholipase A2 (1) Rhinella schneideri (1) Sea anemone (1) Snake venom (1) Snake venom antibacterial peptide (1) Sting (1) Technetium-99m (1) Terminal complement complex (SC5b-9) (1) Mais... Tipo do documento Info:eu-repo/semantics/article (6) Ano 2015 (1) 2009 (1) 2007 (1) 2005 (1) 2002 (1) 2001 (1) Mais... País Brazil (6) Idioma Inglês (6)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 6 Primeira ... 1 ... Última Some toxinological aspects of Aurelia aurita (Linné) from the Mexican Caribbean J. Venom. Anim. Toxins Segura-Puertas,L.; Avila-Soria,G.; Sánchez-Rodríguez,J.; Ramos-Aguilar,M. E.; Burnett,J. W.. Aurelia aurita is a scyphozoan, abundant in the Mexican Caribbean during summer. Although usually innocuous, there is evidence of it causing harm to humans. This work investigates the biological activities of crude and fractionated extracts of A. aurita. Live specimens were collected between July and September 1999 from the Mexican Caribbean. The tentacular margin was dissected immediately and frozen at -50ºC. A nematocyst suspension was prepared, discharged, and the supernatants lyophilized. Hemolytic assay was performed with lyophilized crude extract on bovine, sheep, and human red blood cells. Erythrocyte sensitivity to the toxin was ranked in descending order: human, sheep, and bovine. Toxic activity on Artemia nauplii was evaluated using the same... Tipo: Info:eu-repo/semantics/article Palavras-chave: Aurelia aurita; Sting; Hemolytic activity; Crustacean lethality; Venom. Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302002000200007 Characterization of an antibacterial peptide from indian cobra (Naja naja) venom J. Venom. Anim. Toxins incl. Trop. Dis. Sachidananda,M. K.; Murari,S. K.; Channe Gowda,D.. Due to the development of antibiotic resistance in microorganisms, antimicrobial peptides from natural sources have attracted attention in recent times. Several antimicrobial peptides have been isolated from a wide range of animal sources, particularly snake venoms. Naja naja venom showed antibacterial as well as direct and indirect hemolytic activities, and an antibacterial peptide was purified through gel permeation and ion exchange chromatography. Its molecular mass was 2491Da, which was determined using Matrix Assisted Laser Desorption/Ionization-Time-of-Flight (MALDI-TOF) mass spectrometry and the amino acids sequence of the N-terminus was DEQSTHGAYVWKL. The purified peptide showed potent antibacterial activity against Gram-negative and Gram-positive... Tipo: Info:eu-repo/semantics/article Palavras-chave: Indian cobra; Naja naja; Snake venom antibacterial peptide; Hemolytic activity. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992007000200004 Biological characterization of compounds from Rhinella schneideri poison that act on the complement system J. Venom. Anim. Toxins incl. Trop. Dis. Anjolette,Fernando A. P.; Leite,Flávia P.; Bordon,Karla C. F.; Azzolini,Ana Elisa C. S; Pereira,Juliana C.; Pereira-Crott,Luciana S.; Arantes,Eliane C.. Background The skin secretions of toads of the family Bufonidae contain biogenic amines, alkaloids, steroids (bufotoxins), bufodienolides (bufogenin), peptides and proteins. The poison of Rhinella schneideri, formerly classified as Bufo paracnemis, presents components that act on different biological systems, including the complement system. The aim of this study was to isolate and examine the activity ofRhinella schneideri poison (RsP) components on the complement system.Methods The components active on the complement system were purified in three chromatographic steps, using a combination of cation-exchange, anion-exchange and gel filtration chromatography. The resulting fractions were analyzed by SDS-PAGE and screened for their activity in the hemolytic... Tipo: Info:eu-repo/semantics/article Palavras-chave: Complement system; Hemolytic activity; Neutrophil chemotaxis; Rhinella schneideri; Terminal complement complex (SC5b-9); Toad poison. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992015000100334 In vitro hemolytic activity of Bothrops lanceolatus (fer-de-lance) venom J. Venom. Anim. Toxins incl. Trop. Dis. Martins,LJ; de Araújo,PMF; Bon,C; Hyslop,S; de Araújo,AL. Bothrops lanceolatus venom contains a variety of enzymatic and biological activities. The present work investigated the hemolytic activity of this venom and its phospholipase A2 (PLA2). Bothrops lanceolatus venom (6.7 µg/mL) caused indirect hemolysis of cow, horse, rat and sheep erythrocytes, with horse erythrocytes being the most sensitive; no direct hemolysis was observed. Hemolysis in sheep erythrocytes was concentration-dependent (5-11.7 µg/mL) and markedly attenuated by heating the venom for 30 minutes at ≥ 40°C and by the PLA2 inhibitor p-bromophenacyl bromide. An acidic PLA2 (5 µg/mL) purified from B. lanceolatus venom also caused hemolysis. This PLA2 showed immunoprecipitin lines with antivenom against B. lanceolatus, which suggests that the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Bothrops lanceolatus; Hemolytic activity; Phospholipase A2; Snake venom. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992009000300011 Preparation of crotalus venom radiolabeled with technetium-99m as a tool for biodistribution study BABT Pujatti,Priscilla Brunelli; Simal,Carlos Jorge Rodrigues; Santos,Raquel Gouvêa dos. Technetium-99m (99mTc) has been the radionuclide of choice for nuclear medicine procedures and experimental research. Because of its optimal nuclear properties, 99mTc is suitable for high efficiency detection with the advantage of reduced radiological waste. Crotalus venom (CV) has been shown to reduce tumors in clinical studies and tissue distribution studies are very important for clinical use. The goal of this work was to obtain CV labeled with 99mTc which preserves its biological activity. After labeling, biological activity was assessed by hemolytic activity evaluation. Labeled and crude venom caused indirect hemolysis provided that the incubation medium contained an exogenous source of lecithin. High yield radiolabeled-CV was obtained and biological... Tipo: Info:eu-repo/semantics/article Palavras-chave: Technetium-99m; Labeling; Hemolytic activity. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700002 Identification of hemolytic and neuroactive fractions in the venom of the sea anemone Bunodosoma cangicum BJMBR Lagos,P.; Duran,R.; Cerveñansky,C.; Freitas,J.C.; Silveira,R.. Sea anemones are a rich source of biologically active substances. In crayfish muscle fibers, Bunodosoma cangicum whole venom selectively blocks the I K(Ca) currents. In the present study, we report for the first time powerful hemolytic and neuroactive effects present in two different fractions obtained by gel-filtration chromatography from whole venom of B. cangicum. A cytolytic fraction (Bcg-2) with components of molecular mass ranging from 8 to 18 kDa elicited hemolysis of mouse erythrocytes with an EC50 = 14 µg/ml and a maximum dose of 22 µg/ml. The effects of the neuroactive fraction, Bcg-3 (2 to 5 kDa), were studied on isolated crab nerves. This fraction prolonged the compound action potentials by increasing their duration and rise time in a... Tipo: Info:eu-repo/semantics/article Palavras-chave: Bunodosoma cangicum; Sea anemone; Hemolytic activity; Neurotoxins; Crab nerve. Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000700009 Registros recuperados: 6 Primeira ... 1 ... Última

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